期刊
BIOCHEMICAL SOCIETY TRANSACTIONS
卷 40, 期 -, 页码 821-825出版社
PORTLAND PRESS LTD
DOI: 10.1042/BST20120055
关键词
cisplatin; microRNA (miRNA); protein expression; tumour
资金
- Yorkshire Cancer Research [R/124217-11-1]
Resistance to the cytotoxic effects of cisplatin can be mediated through changes in a wide variety of cellular processes and signalling pathways. The discovery of microRNAs as regulators of protein expression through the targeting of mRNA has led to a number of studies on the effect of cisplatin treatment on microRNA expression, and the ability of microRNAs to modulate cisplatin resistance.
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