The Selective Degradation of Synaptic Connexin 43 Protein by Hypoxia-induced Autophagy Impairs Natural Killer Cell-mediated Tumor Cell Killing

Protein kinase C (PKC) mediated interaction between conexin43 (Cx43) and K+(ATP) channel subunit (Kir6.1) in cardiomyocyte mitochondria: Implications in cytoprotection against hypoxia induced cell apoptosis

(2014) Ajaz Ahmad Waza et al.   CELLULAR SIGNALLING

Tumor Plasticity Interferes with Anti-Tumor Immunity

(2014) Salem Chouaib et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells

(2014) Elisa Mazzini et al.   IMMUNITY

Cell biological steps and checkpoints in accessing NK cell cytotoxicity

(2014) Emily M Mace et al.   IMMUNOLOGY AND CELL BIOLOGY

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

(2014) Vladimir Rogov et al.   MOLECULAR CELL

Probenecid Blocks Human P2X7 Receptor-Induced Dye Uptake via a Pannexin-1 Independent Mechanism

(2014) Archana Bhaskaracharya et al.   PLoS One

Connexin a check-point component of cell apoptosis in normal and physiopathological conditions

(2013) Diane Carette et al.   BIOCHIMIE

Gap Junction Intercellular Communication Mediated by Connexin43 in Astrocytes Is Essential for Their Resistance to Oxidative Stress

(2013) Hoa T. Le et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gap Junction Intercellular Communications Regulate NK Cell Activation and Modulate NK Cytotoxic Capacity

(2013) A. Tittarelli et al.   JOURNAL OF IMMUNOLOGY

Regulation of gap junctions in melanoma and their impact on Melan-A/MART-1-specific CD8+ T lymphocyte emergence

(2013) Houssem Benlalam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

(2013) J. Baginska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting autophagy as a potential therapeutic approach for melanoma therapy

(2013) He Liu et al.   SEMINARS IN CANCER BIOLOGY

Gap junctional communication promotes apoptosis in a connexin-type-dependent manner

(2013) P Kameritsch et al.   Cell Death & Disease

Managing the complexity of communication: regulation of gap junctions by post-translational modification

(2013) Lene N. Axelsen et al.   Frontiers in Pharmacology

Internalized gap junctions are degraded by autophagy

(2012) John T. Fong et al.   Autophagy

Abstract 3906: Design, synthesis and biological evaluation of 2nd generation ezrin inhibitors for metastatic osteosarcoma

(2012) George W. Kosturko et al.   CANCER RESEARCH

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

(2012) M. A. Swartz et al.   CANCER RESEARCH

Isolation of Human CD4/CD8 Double-Positive, Graft-Versus-Host Disease-Protective, Minor Histocompatibility Antigen-Specific Regulatory T Cells and of a Novel HLA-DR7-Restricted HY-Specific CD4 Clone

(2012) A. Eljaafari et al.   JOURNAL OF IMMUNOLOGY

Manipulating Connexin Communication Channels: Use of Peptidomimetics and the Translational Outputs

(2012) W. Howard Evans et al.   JOURNAL OF MEMBRANE BIOLOGY

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

(2012) Eloy Bejarano et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquitin-mediated internalization of connexin43 is independent of the canonical endocytic tyrosine-sorting signal

(2011) Steve Catarino et al.   BIOCHEMICAL JOURNAL

Blocking Hypoxia-Induced Autophagy in Tumors Restores Cytotoxic T-Cell Activity and Promotes Regression

(2011) M. Z. Noman et al.   CANCER RESEARCH

Measurements of Tumor Cell Autophagy Predict Invasiveness, Resistance to Chemotherapy, and Survival in Melanoma

(2011) X.-H. Ma et al.   CLINICAL CANCER RESEARCH

Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome

(2011) Solveig Sirnes et al.   INTERNATIONAL JOURNAL OF CANCER

The gap junction protein Cx43 regulates B-lymphocyte spreading and adhesion

(2011) S. Machtaler et al.   JOURNAL OF CELL SCIENCE

Functional Gap Junctions Accumulate at the Immunological Synapse and Contribute to T Cell Activation

(2011) A. Mendoza-Naranjo et al.   JOURNAL OF IMMUNOLOGY

ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

(2011) Juan A. Orellana et al.   JOURNAL OF NEUROCHEMISTRY

Bacteria-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity

(2010) F. Saccheri et al.   Science Translational Medicine

New views on natural killer cell-based immunotherapy for melanoma treatment

(2010) Shannon Burke et al.   TRENDS IN IMMUNOLOGY

HIF-1: upstream and downstream of cancer metabolism

(2009) Gregg L Semenza   CURRENT OPINION IN GENETICS & DEVELOPMENT

Gap Junctions at the Dendritic Cell-T Cell Interface Are Key Elements for Antigen-Dependent T Cell Activation

(2009) R. Elgueta et al.   JOURNAL OF IMMUNOLOGY

The Cooperative Induction of Hypoxia-Inducible Factor-1  and STAT3 during Hypoxia Induced an Impairment of Tumor Susceptibility to CTL-Mediated Cell Lysis

(2009) M. Z. Noman et al.   JOURNAL OF IMMUNOLOGY

Hypoxia Increases Tumor Cell Shedding of MHC Class I Chain-Related Molecule: Role of Nitric Oxide

(2008) D. R. Siemens et al.   CANCER RESEARCH