标题
Exploring the roles of PALB2 at the crossroads of DNA repair and cancer
作者
关键词
-
出版物
BIOCHEMICAL JOURNAL
Volume 460, Issue 3, Pages 331-342
出版商
Portland Press Ltd.
发表日期
2014-08-05
DOI
10.1042/bj20140208
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Comprehensive sequencing of PALB2 in patients with breast cancer suggests PALB2 mutations explain a subset of hereditary breast cancer
- (2014) Priscilla H. Fernandes et al. CANCER
- PALB2 sequencing in Italian familial breast cancer cases reveals a high-risk mutation recurrent in the province of Bergamo
- (2014) Irene Catucci et al. GENETICS IN MEDICINE
- Integrated analysis of germline and somatic variants in ovarian cancer
- (2014) Krishna L. Kanchi et al. Nature Communications
- Breast Cancer Proteins PALB2 and BRCA2 Stimulate Polymerase η in Recombination-Associated DNA Synthesis at Blocked Replication Forks
- (2014) Rémi Buisson et al. Cell Reports
- Contribution of the PALB2 c.2323C>T [p.Q775X] Founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent
- (2013) Marc Tischkowitz et al. BMC Medical Genetics
- BMN 673, a Novel and Highly Potent PARP1/2 Inhibitor for the Treatment of Human Cancers with DNA Repair Deficiency
- (2013) Y. Shen et al. CLINICAL CANCER RESEARCH
- PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks
- (2013) Michael J. Metzger et al. DNA REPAIR
- Low prevalence of germlinePALB2mutations in Australian triple-negative breast cancer
- (2013) Michelle W. Wong-Brown et al. INTERNATIONAL JOURNAL OF CANCER
- Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair
- (2013) J-Y Park et al. ONCOGENE
- Prevalence of PALB2 Mutations in Breast Cancer Patients in Multi-Ethnic Asian Population in Malaysia and Singapore
- (2013) Sze Yee Phuah et al. PLoS One
- Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer
- (2013) C. Bowman-Colin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA Damage Sensing by the ATM and ATR Kinases
- (2013) A. Marechal et al. Cold Spring Harbor Perspectives in Biology
- Heterozygous mutations in PALB2 cause DNA replication and damage response defects
- (2013) Jenni Nikkilä et al. Nature Communications
- Rare occurrence of PALB2 mutations in ovarian cancer patients from the Volga-Ural region
- (2012) D Prokofyeva et al. CLINICAL GENETICS
- Rare germline mutations inPALB2and breast cancer risk: A population-based study
- (2012) Marc Tischkowitz et al. HUMAN MUTATION
- PALB2 Interacts with KEAP1 To Promote NRF2 Nuclear Accumulation and Function
- (2012) J. Ma et al. MOLECULAR AND CELLULAR BIOLOGY
- PALB2 self-interaction controls homologous recombination
- (2012) Rémi Buisson et al. NUCLEIC ACIDS RESEARCH
- RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination
- (2012) B H Lok et al. ONCOGENE
- Mutation Analysis of BRCA1, BRCA2, PALB2 and BRD7 in a Hospital-Based Series of German Patients with Triple-Negative Breast Cancer
- (2012) Franziska Pern et al. PLoS One
- BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer
- (2011) Michelle W. Wong et al. BREAST CANCER RESEARCH AND TREATMENT
- Detection of a large rearrangement in PALB2 in Spanish breast cancer families with male breast cancer
- (2011) Ana Blanco et al. BREAST CANCER RESEARCH AND TREATMENT
- Novel germline PALB2 truncating mutations in African American breast cancer patients
- (2011) Yonglan Zheng et al. CANCER
- Contribution of Inherited Mutations in the BRCA2-Interacting Protein PALB2 to Familial Breast Cancer
- (2011) S. Casadei et al. CANCER RESEARCH
- ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair
- (2011) Jean-Yves Bleuyard et al. EMBO REPORTS
- PALB2 mutations in familial breast and pancreatic cancer
- (2011) Erin W. Hofstatter et al. Familial Cancer
- Ubiquitylation and the Fanconi anemia pathway
- (2011) Elizabeth Garner et al. FEBS LETTERS
- BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
- (2011) A. V. Nimonkar et al. GENES & DEVELOPMENT
- Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
- (2011) S. E. Polo et al. GENES & DEVELOPMENT
- Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer
- (2011) Heide Hellebrand et al. HUMAN MUTATION
- Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression
- (2011) Peter Bouwman et al. JOURNAL OF PATHOLOGY
- Using mouse models to investigate the biological and physiological consequences of defects in the Fanconi anaemia/breast cancer DNA repair signalling pathway
- (2011) Marc Tischkowitz et al. JOURNAL OF PATHOLOGY
- Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination
- (2011) Kyosuke Nakamura et al. MOLECULAR CELL
- Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks
- (2011) Lilach Moyal et al. MOLECULAR CELL
- Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction
- (2011) Beat Fierz et al. Nature Chemical Biology
- Chfr and RNF8 synergistically regulate ATM activation
- (2011) Jiaxue Wu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
- (2011) T. Walsh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plasticity of BRCA2 Function in Homologous Recombination: Genetic Interactions of the PALB2 and DNA Binding Domains
- (2011) Nicolas Siaud et al. PLoS Genetics
- A novel germline PALB2 deletion in Polish breast and ovarian cancer patients
- (2010) Agnieszka Dansonka-Mieszkowska et al. BMC Medical Genetics
- PALB2 analysis in BRCA2-like families
- (2010) M. A. Adank et al. BREAST CANCER RESEARCH AND TREATMENT
- PALB2 mutations in German and Russian patients with bilateral breast cancer
- (2010) Natalia Bogdanova et al. BREAST CANCER RESEARCH AND TREATMENT
- Mutations in BRCA2 and PALB2 in male breast cancer cases from the United States
- (2010) Yuan Chun Ding et al. BREAST CANCER RESEARCH AND TREATMENT
- PALB2 germline mutations in familial breast cancer cases with personal and family history of pancreatic cancer
- (2010) Paolo Peterlongo et al. BREAST CANCER RESEARCH AND TREATMENT
- PALB2/FANCN: Recombining Cancer and Fanconi Anemia
- (2010) M. Tischkowitz et al. CANCER RESEARCH
- PALB2 mutations in European familial pancreatic cancer families
- (2010) EP Slater et al. CLINICAL GENETICS
- PALB2: a novel inactivating mutation in a Italian breast cancer family
- (2010) Cristina Balia et al. Familial Cancer
- Expanded roles of the Fanconi anemia pathway in preserving genomic stability
- (2010) Y. Kee et al. GENES & DEVELOPMENT
- Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice
- (2010) Pia Rantakari et al. HUMAN MOLECULAR GENETICS
- MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks
- (2010) T. Hayakawa et al. JOURNAL OF CELL SCIENCE
- Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer
- (2010) M. C. Villarroel et al. MOLECULAR CANCER THERAPEUTICS
- Purified human BRCA2 stimulates RAD51-mediated recombination
- (2010) Ryan B. Jensen et al. NATURE
- Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
- (2010) Mary Ellen Moynahan et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA
- (2010) Jie Liu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA
- (2010) Tina Thorslund et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination
- (2010) Rémi Buisson et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
- (2010) Eloïse Dray et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Rad52 inactivation is synthetically lethal with BRCA2 deficiency
- (2010) Z. Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- How the Fanconi Anemia Pathway Guards the Genome
- (2009) George-Lucian Moldovan et al. Annual Review of Genetics
- The Breast Cancer Susceptibility Mutation PALB2 1592delT Is Associated with an Aggressive Tumor Phenotype
- (2009) T. Heikkinen et al. CLINICAL CANCER RESEARCH
- PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response
- (2009) Feng Zhang et al. CURRENT BIOLOGY
- Structural basis for recruitment of BRCA2 by PALB2
- (2009) Antony W Oliver et al. EMBO REPORTS
- A PALB2 germline mutation associated with hereditary breast cancer in Italy
- (2009) Laura Papi et al. Familial Cancer
- PALB2 sequence variants in young South African breast cancer patients
- (2009) Michelle Sluiter et al. Familial Cancer
- Analysis of the Gene Coding for the BRCA2-Interacting Protein PALB2 in Familial and Sporadic Pancreatic Cancer
- (2009) Marc D. Tischkowitz et al. GASTROENTEROLOGY
- MRG15 Is a Novel PALB2-interacting Factor Involved in Homologous Recombination
- (2009) Shirley M.-H. Sy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PALB2 Regulates Recombinational Repair through Chromatin Association and Oligomerization
- (2009) Shirley M.-H. Sy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2
- (2009) F. Zhang et al. MOLECULAR CANCER RESEARCH
- PALB2 is an integral component of the BRCA complex required for homologous recombination repair
- (2009) S. M. H. Sy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene
- (2009) S. Jones et al. SCIENCE
- Mechanism of Eukaryotic Homologous Recombination
- (2008) Joseph San Filippo et al. Annual Review of Biochemistry
- The prevalence of PALB2 germline mutations in BRCA1/BRCA2 negative Chinese women with early onset breast cancer or affected relatives
- (2008) A-Yong Cao et al. BREAST CANCER RESEARCH AND TREATMENT
- Analysis of FANCB and FANCN/PALB2 Fanconi Anemia genes in BRCA1/2-negative Spanish breast cancer families
- (2008) María J. García et al. BREAST CANCER RESEARCH AND TREATMENT
- Penetrance Analysis of the PALB2 c.1592delT Founder Mutation
- (2008) H. Erkko et al. CLINICAL CANCER RESEARCH
- Inherited Susceptibility to Common Cancers
- (2008) William D. Foulkes NEW ENGLAND JOURNAL OF MEDICINE
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