ROS inhibitorN-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors

Piperlongumine induces inhibition of the ubiquitin–proteasome system in cancer cells

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Proteasome Inhibitors: An Expanding Army Attacking a Unique Target

(2012) Alexei F. Kisselev et al.   CHEMISTRY & BIOLOGY

Proteasome inhibitor MG-132 induces C6 glioma cell apoptosis via oxidative stress

(2011) Wen-hai Fan et al.   ACTA PHARMACOLOGICA SINICA

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

(2011) Lakshmi Raj et al.   NATURE

The transcription factor FOXM1 is a cellular target of the natural product thiostrepton

(2011) Nagaratna S. Hegde et al.   Nature Chemistry

Proteasome inhibitors in cancer therapy

(2011) Lisa J. Crawford et al.   Journal of Cell Communication and Signaling

N-acetylcysteine, reactive oxygen species and beyond

(2010) Shi-Yong Sun   CANCER BIOLOGY & THERAPY

A new target for proteasome inhibitors: FoxM1

(2010) Andrei L Gartel   EXPERT OPINION ON INVESTIGATIONAL DRUGS

FoxM1, a critical regulator of oxidative stress during oncogenesis

(2009) Hyun Jung Park et al.   EMBO JOURNAL

Covalent complexes of proteasome model with peptide aldehyde inhibitors MG132 and MG101: docking and molecular dynamics study

(2009) Siwei Zhang et al.   JOURNAL OF MOLECULAR MODELING

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

(2009) Zachary T. Schafer et al.   NATURE

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Thiazole Antibiotics Target FoxM1 and Induce Apoptosis in Human Cancer Cells

(2009) Uppoor G. Bhat et al.   PLoS One

FoxM1 Is a General Target for Proteasome Inhibitors

(2009) Uppoor G. Bhat et al.   PLoS One

Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment

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Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL