Generation and characterization of a lysosomally targeted, genetically encoded Ca2+-sensor

Structural and functional conservation of key domains in InsP3 and ryanodine receptors

(2012) Min-Duk Seo et al.   NATURE

Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release

(2012) Dongbiao Shen et al.   Nature Communications

Molecular mechanisms of endolysosomal Ca2+signalling in health and disease

(2011) Anthony J. Morgan et al.   BIOCHEMICAL JOURNAL

NAADP links histamine H1 receptors to secretion of von Willebrand factor in human endothelial cells

(2011) B. Esposito et al.   BLOOD

Lysosomal Ca2+ homeostasis: Role in pathogenesis of lysosomal storage diseases

(2011) Emyr Lloyd-Evans et al.   CELL CALCIUM

Signaling complexes of voltage-gated calcium channels

(2011) Ray W. Turner et al.   Channels

Determination of the Membrane Topology of the Small EF-Hand Ca2+-Sensing Proteins CaBP7 and CaBP8

(2011) Hannah V. McCue et al.   PLoS One

NAADP as an intracellular messenger regulating lysosomal calcium-release channels

(2010) Antony Galione et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals

(2010) Sandip Patel et al.   CELL CALCIUM

The Ecto-enzyme CD38 Is a Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Synthase That Couples Receptor Activation to Ca2+Mobilization from Lysosomes in Pancreatic Acinar Cells

(2010) François Cosker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Deficits in a Neuronal Calcium Sensor-1 Mutant Identified in a Case of Autistic Spectrum Disorder

(2010) Mark T. W. Handley et al.   PLoS One

Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channels

(2010) P. K. Aley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The proteome of lysosomes

(2010) Bernd A. Schröder et al.   PROTEOMICS

Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling

(2010) Sandip Patel et al.   TRENDS IN CELL BIOLOGY

Ryanodine Receptors: Structure, Expression, Molecular Details, and Function in Calcium Release

(2010) J. T. Lanner et al.   Cold Spring Harbor Perspectives in Biology

Calcium signaling via two-pore channels: local or global, that is the question

(2009) Michael X. Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

(2009) Eugen Brailoiu et al.   JOURNAL OF CELL BIOLOGY

NAADP mobilizes calcium from acidic organelles through two-pore channels

(2009) Peter J. Calcraft et al.   NATURE

Identification of a chemical probe for NAADP by virtual screening

(2009) Edmund Naylor et al.   Nature Chemical Biology

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

(2009) Lin Tian et al.   NATURE METHODS

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS