Heat-shock factor 1 both positively and negatively affects cellular clonogenic growth depending on p53 status

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

(2012) Marc L. Mendillo et al.   CELL

Heat stress induces epithelial plasticity and cell migration independent of heat shock factor 1

(2012) B. J. Lang et al.   CELL STRESS & CHAPERONES

HSF1, A Versatile Factor in Tumorogenesis

(2012) S.K. Calderwood   CURRENT MOLECULAR MEDICINE

Heat Shock Factor Hsf1 Cooperates with ErbB2 (Her2/Neu) Protein to Promote Mammary Tumorigenesis and Metastasis

(2012) Caixia Xi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The evolving concept of cancer and metastasis stem cells

(2012) Irène Baccelli et al.   JOURNAL OF CELL BIOLOGY

Using the Heat-Shock Response To Discover Anticancer Compounds that Target Protein Homeostasis

(2011) Sandro Santagata et al.   ACS Chemical Biology

Selection of Brain Metastasis-Initiating Breast Cancer Cells Determined by Growth on Hard Agar

(2011) Lixia Guo et al.   AMERICAN JOURNAL OF PATHOLOGY

Heat shock factor 1 promotes invasion and metastasis of hepatocellular carcinoma in vitro and in vivo

(2011) Feng Fang et al.   CANCER

p53 and its mutants in tumor cell migration and invasion

(2011) Patricia A. J. Muller et al.   JOURNAL OF CELL BIOLOGY

Functional Inactivation of Endogenous MDM2 and CHIP by HSP90 Causes Aberrant Stabilization of Mutant p53 in Human Cancer Cells

(2011) D. Li et al.   MOLECULAR CANCER RESEARCH

High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

(2011) S. Santagata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of heat shock factor-1 activation in the doxorubicin-induced heart failure in mice

(2010) Kaushik Vedam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

High Aldehyde Dehydrogenase Activity Identifies Tumor-Initiating and Metastasis-Initiating Cells in Human Prostate Cancer

(2010) Christel van den Hoogen et al.   CANCER RESEARCH

AACR Centennial Series: The Biology of Cancer Metastasis: Historical Perspective

(2010) J. E. Talmadge et al.   CANCER RESEARCH

P53 is transported into the nucleus via an Hsf1-dependent nuclear localization mechanism

(2010) Qiang Li et al.   MOLECULAR CARCINOGENESIS

Heat shock factors: integrators of cell stress, development and lifespan

(2010) Malin Åkerfelt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Roles of heat shock factor 1 and 2 in response to proteasome inhibition: consequence on p53 stability

(2010) S Lecomte et al.   ONCOGENE

Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis

(2010) L Meng et al.   ONCOGENE

Inhibiting the transcription factor HSF1 as an anticancer strategy

(2009) Luke Whitesell et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Heat shock factor 1 deficiency via its downstream target gene αB-crystallin (Hspb5) impairs p53 degradation

(2009) Xiongjie Jin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Heat shock factor-1 modulates p53 activity in the transcriptional response to DNA damage

(2009) Ian R. Logan et al.   NUCLEIC ACIDS RESEARCH

Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data

(2009) J. M. Ruijter et al.   NUCLEIC ACIDS RESEARCH

Mouse Heat-Shock Factor 1 (HSF1) Is Involved in Testicular Response to Genotoxic Stress Induced by Doxorubicin1

(2008) Pierre A. Salmand et al.   BIOLOGY OF REPRODUCTION

Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling

(2008) L E Dow et al.   ONCOGENE