Hepatic triacylglycerol synthesis and secretion: DGAT2 as the link between glycaemia and triglyceridaemia

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

A Ceramide-Centric View of Insulin Resistance

(2012) Jose A. Chavez et al.   Cell Metabolism

Association Between Nonalcoholic Fatty Liver Disease and Risk for Hepatocellular Cancer, Based on Systematic Review

(2012) Donna L. White et al.   Clinical Gastroenterology and Hepatology

Diacylglycerol acyltransferase 2 acts upstream of diacylglycerol acyltransferase 1 and utilizes nascent diglycerides andde novosynthesized fatty acids in HepG2 cells

(2012) Haja R. Wurie et al.   FEBS Journal

Lipid-dependent Generation of Dual Topology for a Membrane Protein

(2012) Mikhail Bogdanov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The FATP1–DGAT2 complex facilitates lipid droplet expansion at the ER–lipid droplet interface

(2012) Ningyi Xu et al.   JOURNAL OF CELL BIOLOGY

Lipid droplet formation on opposing sides of the endoplasmic reticulum

(2012) Stephen L. Sturley et al.   JOURNAL OF LIPID RESEARCH

Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying

(2012) Gene P. Ables et al.   JOURNAL OF LIPID RESEARCH

Liver fat reduction with niacin is influenced byDGAT-2polymorphisms in hypertriglyceridemic patients

(2012) Miao Hu et al.   JOURNAL OF LIPID RESEARCH

The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2

(2012) Jenson Qi et al.   JOURNAL OF LIPID RESEARCH

Molecular genetic and biochemical approaches for defining lipid-dependent membrane protein folding

(2011) William Dowhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

(2011) F. Amati et al.   DIABETES

Packaging of Fat: An Evolving Model of Lipid Droplet Assembly and Expansion

(2011) Dawn L. Brasaemle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence That Diacylglycerol Acyltransferase 1 (DGAT1) Has Dual Membrane Topology in the Endoplasmic Reticulum of HepG2 Cells

(2011) Haja R. Wurie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes

(2011) Charles A. Harris et al.   JOURNAL OF LIPID RESEARCH

Hydrophobic-Domain-Dependent Protein-Protein Interactions Mediate the Localization of GPAT Enzymes to ER Subdomains

(2011) Satinder K. Gidda et al.   TRAFFIC

Role of endoplasmic reticulum neutral lipid hydrolases

(2011) Ariel D. Quiroga et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Topological Orientation of Acyl-CoA:Diacylglycerol Acyltransferase-1 (DGAT1) and Identification of a Putative Active Site Histidine and the Role of the N Terminus in Dimer/Tetramer Formation

(2010) Pamela J. McFie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation

(2010) Ni-Huiping Son et al.   JOURNAL OF CLINICAL INVESTIGATION

Intestine-specific expression of acyl CoA:diacylglycerol acyltransferase 1 reverses resistance to diet-induced hepatic steatosis and obesity inDgat1−/−mice

(2010) Bonggi Lee et al.   JOURNAL OF LIPID RESEARCH

Altered Lipid Droplet Dynamics in Hepatocytes Lacking Triacylglycerol Hydrolase Expression

(2010) Huajin Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Diacylglycerol-mediated insulin resistance

(2010) Derek M Erion et al.   NATURE MEDICINE

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity

(2009) Matthew T. Flowers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids

(2009) Claudio J. Villanueva et al.   HEPATOLOGY

DGAT1 Expression Increases Heart Triglyceride Content but Ameliorates Lipotoxicity

(2009) Li Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited

(2008) John J. Dubé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Postprandial dyslipidemia in insulin resistance: Mechanisms and role of intestinal insulin sensitivity

(2008) Joanne Hsieh et al.   ATHEROSCLEROSIS SUPPLEMENTS

Hepatic Insulin Resistance Is Sufficient to Produce Dyslipidemia and Susceptibility to Atherosclerosis

(2008) Sudha B. Biddinger et al.   Cell Metabolism

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with Mitochondria

(2008) Scot J. Stone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regions of Melanocortin 2 (MC2) Receptor Accessory Protein Necessary for Dual Topology and MC2 Receptor Trafficking and Signaling

(2008) Julien A. Sebag et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of Antiparallel Two-domain Membrane Proteins: Tracing Multiple Gene Duplication Events in the DUF606 Family

(2008) Juke S. Lolkema et al.   JOURNAL OF MOLECULAR BIOLOGY

Diacylglycerol acyltransferases: Potential roles as pharmacological targets

(2008) Victor A. Zammit et al.   PHARMACOLOGY & THERAPEUTICS

Imaging of Lipid Biosynthesis: How a Neutral Lipid Enters Lipid Droplets

(2008) Lars Kuerschner et al.   TRAFFIC