Mitochondrial respiratory chain complex I is inactivated by NADPH oxidase Nox4

The ROS-NOX Connection in Cancer and Angiogenesis

(2012) Christophe Blanchetot et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Mitochondrial morphology—emerging role in bioenergetics

(2012) Chad A. Galloway et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial ROS production under cellular stress: comparison of different detection methods

(2011) Andrey V. Kuznetsov et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Mitochondrial complex III stabilizes complex I in the absence of NDUFS4 to provide partial activity

(2011) M. A. Calvaruso et al.   HUMAN MOLECULAR GENETICS

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

(2011) U Weyemi et al.   ONCOGENE

Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain

(2010) Yukio Nisimoto et al.   BIOCHEMISTRY

NADPH oxidase 4 is an oncoprotein localized to mitochondria

(2010) Kelly A. Graham et al.   CANCER BIOLOGY & THERAPY

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

(2010) Tetsuro Ago et al.   CIRCULATION RESEARCH

Ageing alters the supramolecular architecture of OxPhos complexes in rat brain cortex

(2010) Monika Frenzel et al.   EXPERIMENTAL GERONTOLOGY

Downstream Targets and Intracellular Compartmentalization in Nox Signaling

(2009) Kai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Cross-Talk Between Mitochondria and NADPH Oxidase: Effects of Mild Mitochondrial Dysfunction on Angiotensin II-Mediated Increase in Nox Isoform Expression and Activity in Vascular Smooth Muscle Cells

(2009) João Wosniak et al.   ANTIOXIDANTS & REDOX SIGNALING

NADPH Oxidases: Functions and Pathologies in the Vasculature

(2009) Bernard Lassègue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells

(2009) Barbara Lener et al.   BIOCHEMICAL JOURNAL

Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells

(2009) Alicia N. Lyle et al.   CIRCULATION RESEARCH

Regulation of cell proliferation by NADPH oxidase-mediated signaling: Potential roles in tissue repair, regenerative medicine and tissue engineering

(2009) Elsa C. Chan et al.   PHARMACOLOGY & THERAPEUTICS

Subcellular localization of Nox4 and regulation in diabetes

(2009) K. Block et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The changing shape of mitochondrial apoptosis

(2009) Michał Wasilewski et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Nox4 Acts as a Switch Between Differentiation and Proliferation in Preadipocytes

(2008) Katrin Schröder et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells

(2008) D. Meng et al.   CARDIOVASCULAR RESEARCH

Differential vascular functions of Nox family NADPH oxidases

(2008) Ralf P Brandes et al.   CURRENT OPINION IN LIPIDOLOGY

Nox4 NAD(P)H Oxidase Mediates Src-dependent Tyrosine Phosphorylation of PDK-1 in Response to Angiotensin II

(2008) Karen Block et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Localization of PTP-1B, SHP-2, and Src Exclusively in Rat Brain Mitochondria and Functional Consequences

(2008) Amal Arachiche et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of ROS signal transduction by NADPH oxidase 4 localization

(2008) Kai Chen et al.   JOURNAL OF CELL BIOLOGY

The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics

(2008) Jon O. Lundberg et al.   NATURE REVIEWS DRUG DISCOVERY

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

(2008) Philippe A. Parone et al.   PLoS One