Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity: A Possible Contributor to Increased Risk of Cardiovascular Disease in Diabetes

(2011) N. Rabbani et al.   DIABETES

Fisetin Lowers Methylglyoxal Dependent Protein Glycation and Limits the Complications of Diabetes

(2011) Pamela Maher et al.   PLoS One

Glyoxalase in diabetes, obesity and related disorders

(2011) Naila Rabbani et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Glyoxalase in ageing

(2011) Mingzhan Xue et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Nrf2–Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO)

(2010) Martin E. Rinaldi Tosi et al.   CELL STRESS & CHAPERONES

Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress

(2010) Alexander Kurz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy

(2010) T. Jiang et al.   DIABETES

Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes

(2010) N. Karachalias et al.   DIABETOLOGIA

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

(2010) O. Brouwers et al.   DIABETOLOGIA

Overexpression of Glyoxalase-I Reduces Hyperglycemia-induced Levels of Advanced Glycation End Products and Oxidative Stress in Diabetic Rats

(2010) Olaf Brouwers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Proteomic View on the Role of Glucose in Peritoneal Dialysis

(2010) Michael Lechner et al.   JOURNAL OF PROTEOME RESEARCH

Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance

(2010) Paul J. Thornalley et al.   NUCLEIC ACIDS RESEARCH

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands

(2009) D. Yao et al.   DIABETES

Advanced Glycation End Products in Extracellular Matrix Proteins Contribute to the Failure of Sensory Nerve Regeneration in Diabetes

(2009) Beatriz Duran-Jimenez et al.   DIABETES

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

(2008) Michael Morcos et al.   AGING CELL

The Dicarbonyl Proteome

(2008) Naila Rabbani et al.   Annals of the New York Academy of Sciences

Reversal of Hyperglycemia-Induced Angiogenesis Deficit of Human Endothelial Cells by Overexpression of Glyoxalase 1In Vitro

(2008) Usman Ahmed et al.   Annals of the New York Academy of Sciences

Dicarbonyl-induced accelerated aging in vitro in human skin fibroblasts

(2008) Henrik Sejersen et al.   BIOGERONTOLOGY

Decreasing Intracellular Superoxide Corrects Defective Ischemia-induced New Vessel Formation in Diabetic Mice

(2008) Daniel J. Ceradini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ordered Organelle Degradation during Starvation-induced Autophagy

(2008) Anders Riis Kristensen et al.   MOLECULAR & CELLULAR PROTEOMICS

Nuclear factor erythroid 2-related factor 2 protects against beta amyloid

(2008) Katja Kanninen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE