A non-B DNA can replace heptamer of V(D)J recombination when present along with a nonamer: implications in chromosomal translocations and cancer

Mechanism of Fragility atBCL2Gene Minor Breakpoint Cluster Region during t(14;18) Chromosomal Translocation

(2012) Mridula Nambiar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

V(D)J Recombination: Mechanisms of Initiation

(2011) David G. Schatz et al.   Annual Review of Genetics

Synergistic requirement of orphan nonamer-like elements and DNA bending enhanced by HMGB1 for RAG-mediated nicking at cryptic 12-RSS but not authentic 12-RSS

(2011) Masashi Numata et al.   GENES TO CELLS

Differential Reaction Kinetics, Cleavage Complex Formation, and Nonamer Binding Domain Dependence Dictate the Structure-Specific and Sequence-Specific Nuclease Activity of RAGs

(2011) Abani Kanta Naik et al.   JOURNAL OF MOLECULAR BIOLOGY

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Cytosines, but Not Purines, Determine Recombination Activating Gene (RAG)-induced Breaks on Heteroduplex DNA Structures

(2010) Abani Kanta Naik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-apoptotic Protein BCL2 Down-regulates DNA End Joining in Cancer Cells

(2010) Tadi Satish Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma

(2010) Mridula Nambiar et al.   NUCLEIC ACIDS RESEARCH

HMGB1/2 can target DNA for illegitimate cleavage by the RAG1/2 complex

(2009) Ming Zhang et al.   BMC MOLECULAR BIOLOGY

Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis

(2009) Fang Fang Yin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for Their Lineage and Stage Specificity

(2008) Albert G. Tsai et al.   CELL

P1 nuclease cleavage is dependent on length of the mismatches in DNA

(2008) Abani Kanta Naik et al.   DNA REPAIR

V(D)J Recombinase Binding and Cleavage of Cryptic Recombination Signal Sequences Identified from Lymphoid Malignancies

(2008) Ming Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The DNA-encoded nucleosome organization of a eukaryotic genome

(2008) Noam Kaplan et al.   NATURE

An Immunodeficiency Disease withRAGMutations and Granulomas

(2008) Catharina Schuetz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence for Ku70/Ku80 association with full-length RAG1

(2008) Prafulla Raval et al.   NUCLEIC ACIDS RESEARCH