Isoform-selective induction of human p110δ PI3K expression by TNFα: identification of a new and induciblePIK3CDpromoter

PI3 Kinase δ Is a Key Regulator of Synoviocyte Function in Rheumatoid Arthritis

(2012) Beatrix Bartok et al.   AMERICAN JOURNAL OF PATHOLOGY

MT1-MMP regulates the PI3K {middle dot}Mi-2/NuRD-dependent control of macrophage immune function

(2012) R. Shimizu-Hirota et al.   GENES & DEVELOPMENT

A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells

(2011) M. Bombardieri et al.   ANNALS OF THE RHEUMATIC DISEASES

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

(2011) Poulikos I. Poulikakos et al.   NATURE

PI3K pathway inhibitors approach junction

(2011) David Holmes   NATURE REVIEWS DRUG DISCOVERY

A promoter DNA demethylation landscape of human hematopoietic differentiation

(2011) Vincenzo Calvanese et al.   NUCLEIC ACIDS RESEARCH

p37δ is a new isoform of PI3K p110δ that increases cell proliferation and is overexpressed in tumors

(2011) S Fransson et al.   ONCOGENE

Inhibition of PI3K Prevents the Proliferation and Differentiation of Human Lung Fibroblasts into Myofibroblasts: The Role of Class I P110 Isoforms

(2011) Enrico Conte et al.   PLoS One

PI3K  Inhibitors in Cancer: Rationale and Serendipity Merge in the Clinic

(2011) D. A. Fruman et al.   Cancer Discovery

Phosphatidylinositol 3-kinase-δ up-regulates L-type Ca2+ currents and increases vascular contractility in a mouse model of type 1 diabetes

(2010) JF Pinho et al.   BRITISH JOURNAL OF PHARMACOLOGY

Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion

(2010) Pei Ching Low et al.   JOURNAL OF CELL BIOLOGY

RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia

(2009) H. Edwards et al.   BLOOD

Histone modifications at human enhancers reflect global cell-type-specific gene expression

(2009) Nathaniel D. Heintzman et al.   NATURE

The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules

(2009) Shengli Hao et al.   NATURE IMMUNOLOGY

Regulation of p110δ PI 3-Kinase Gene Expression

(2009) Klaartje Kok et al.   PLoS One

Shedding light on class I phosphoinositide 3-kinase activity in endothelium

(2008) T. M. Randis et al.   BLOOD