Effects of a glucokinase activator on hepatic intermediary metabolism: study with13C-isotopomer-based metabolomics

Down-regulation of Hepatic Urea Synthesis by Oxypurines

(2011) Itzhak Nissim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Triglyceride Response to an Intensive Lifestyle Intervention Is Enhanced in Carriers of theGCKRPro446Leu Polymorphism

(2011) Toni I. Pollin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effect of long-term treatment with a small-molecule glucokinase activator on glucose metabolism, lipid profiles and hepatic function

(2011) Akinobu Nakamura et al.   Journal of Diabetes Investigation

Glucokinase-activating GCKR Polymorphisms Increase Plasma Levels of Triglycerides and Free Fatty Acids, but do not Elevate Cardiovascular Risk in the Ludwigshafen Risk and Cardiovascular Health Study

(2010) D. H. Kozian et al.   HORMONE AND METABOLIC RESEARCH

Recent advances in glucokinase activators for the treatment of type 2 diabetes

(2009) Manojit Pal   DRUG DISCOVERY TODAY

Assessing the potential of glucokinase activators in diabetes therapy

(2009) Franz M. Matschinsky   NATURE REVIEWS DRUG DISCOVERY

Glucokinase and molecular aspects of liver glycogen metabolism

(2008) Loranne Agius   BIOCHEMICAL JOURNAL

Restoration of Hepatic Glucokinase Expression Corrects Hepatic Glucose Flux and Normalizes Plasma Glucose in Zucker Diabetic Fatty Rats

(2008) T. P. Torres et al.   DIABETES

Targeting Hepatic Glucokinase in Type 2 Diabetes: Weighing the Benefits and Risks

(2008) L. Agius   DIABETES

Impact of Small-Molecule Glucokinase Activator on Glucose Metabolism and β-Cell Mass

(2008) Akinobu Nakamura et al.   ENDOCRINOLOGY

Elimination of KATPChannels in Mouse Islets Results in Elevated [U-13C]Glucose Metabolism, Glutaminolysis, and Pyruvate Cycling but a Decreased γ-Aminobutyric Acid Shunt

(2008) Changhong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

3-Isobutylmethylxanthine Inhibits Hepatic Urea Synthesis

(2008) Itzhak Nissim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolomic and Mass Isotopomer Analysis of Liver Gluconeogenesis and Citric Acid Cycle

(2008) Lili Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human carbamoyl-phosphate synthetase: Insight into N-acetylglutamate interaction and the functional effects of a common single nucleotide polymorphism

(2008) V. Ahuja et al.   JOURNAL OF INHERITED METABOLIC DISEASE