Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism

Cellular Redox Pathways as a Therapeutic Target in the Treatment of Cancer

(2011) Alberto J. Montero et al.   DRUGS

Selenodiglutathione uptake by the Saccharomyces cerevisiae vacuolar ATP-binding cassette transporter Ycf1p

(2011) Myriam Lazard et al.   FEBS Journal

Thioredoxin and thioredoxin reductase: Current research with special reference to human disease

(2010) Arne Holmgren et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets

(2010) Anton A. Turanov et al.   BIOCHEMICAL JOURNAL

Thioredoxin reductase 1 knockdown enhances selenazolidine cytotoxicity in human lung cancer cells via mitochondrial dysfunction

(2010) Robyn L. Poerschke et al.   BIOCHEMICAL PHARMACOLOGY

Deficiency in the 15-kDa Selenoprotein Inhibits Tumorigenicity and Metastasis of Colon Cancer Cells

(2010) R. Irons et al.   Cancer Prevention Research

Loss of Thioredoxin Reductase 1 Renders Tumors Highly Susceptible to Pharmacologic Glutathione Deprivation

(2010) P. K. Mandal et al.   CANCER RESEARCH

Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture

(2010) Carolin S. Hoefig et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Selenium and the Selenoprotein Thioredoxin Reductase in the Prevention, Treatment and Diagnostics of Cancer

(2009) Markus Selenius et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation and function of selenoproteins in human disease

(2009) Frederick P. Bellinger et al.   BIOCHEMICAL JOURNAL

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase

(2009) Valentina Gandin et al.   BIOCHEMICAL PHARMACOLOGY

Selenoproteins that function in cancer prevention and promotion

(2009) Dolph L. Hatfield et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Outcome of Selenium and Vitamin E Cancer Prevention Trial (SELECT) Reveals the Need for Better Understanding of Selenium Biology

(2009) D. L. Hatfield et al.   MOLECULAR INTERVENTIONS

Potent Activity of Indolequinones against Human Pancreatic Cancer: Identification of Thioredoxin Reductase as a Potential Target

(2009) C. Yan et al.   MOLECULAR PHARMACOLOGY

Cytoprotective Nrf2 Pathway Is Induced In Chronically Txnrd 1-Deficient Hepatocytes

(2009) Elena S. Suvorova et al.   PLoS One

Extracellular thiol-assisted selenium uptake dependent on the xc- cystine transporter explains the cancer-specific cytotoxicity of selenite

(2009) E. Olm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selenium Compounds and Selenoproteins in Cancer

(2008) Regina Brigelius-Flohé   CHEMISTRY & BIODIVERSITY

Thioredoxin Reductase-1 Negatively Regulates HIV-1 Transactivating Protein Tat-dependent Transcription in Human Macrophages

(2008) Parisa Kalantari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY