The role of TBK1 and IKKϵ in the expression and activation of Pellino 1

Novel cross-talk within the IKK family controls innate immunity

(2011) Kristopher Clark et al.   BIOCHEMICAL JOURNAL

Quantitative Analysis of Kinase-Proximal Signaling in Lipopolysaccharide-Induced Innate Immune Response

(2010) Kirti Sharma et al.   JOURNAL OF PROTEOME RESEARCH

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

MSK1 regulates the transcription of IL-1ra in response to TLR activation in macrophages

(2009) Joanne Darragh et al.   BIOCHEMICAL JOURNAL

Use of the Pharmacological Inhibitor BX795 to Study the Regulation and Physiological Roles of TBK1 and IκB Kinase ϵ

(2009) Kristopher Clark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of the Tumor Suppressor CYLD by the Breast Cancer Oncogene IKKɛ Promotes Cell Transformation

(2009) Jessica E. Hutti et al.   MOLECULAR CELL

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

(2009) Mikyoung Chang et al.   NATURE IMMUNOLOGY

Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4

(2009) H. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Manipulation of immune system via immortal bone marrow stem cells

(2008) C. Ruedl et al.   INTERNATIONAL IMMUNOLOGY

Lys63-Linked Polyubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF- B Activation

(2008) D. B. Conze et al.   MOLECULAR AND CELLULAR BIOLOGY

Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL-1 Receptor-Associated Kinase 1 To Facilitate NEMO Binding and the Activation of I B  Kinase

(2008) M. Windheim et al.   MOLECULAR AND CELLULAR BIOLOGY

Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2

(2008) Tatsukata Kawagoe et al.   NATURE IMMUNOLOGY

Pellino Proteins Contain a Cryptic FHA Domain that Mediates Interaction with Phosphorylated IRAK1

(2008) Chun-Chi Lin et al.   STRUCTURE

The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1

(2007) Alban Ordureau et al.   BIOCHEMICAL JOURNAL