标题
Mutational analysis of allosteric activation and inhibition of glucokinase
作者
关键词
-
出版物
BIOCHEMICAL JOURNAL
Volume 440, Issue 2, Pages 203-215
出版商
Portland Press Ltd.
发表日期
2011-08-11
DOI
10.1042/bj20110440
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Generation ofN-Ethyl-N-nitrosourea (ENU) Diabetes Models in Mice Demonstrates Genotype-specific Action of Glucokinase Activators
- (2011) Deborah Fenner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Direct Evidence of Conformational Heterogeneity in Human Pancreatic Glucokinase from High-Resolution Nuclear Magnetic Resonance
- (2010) Mioara Larion et al. BIOCHEMISTRY
- Global Fit Analysis of Glucose Binding Curves Reveals a Minimal Model for Kinetic Cooperativity in Human Glucokinase
- (2010) Mioara Larion et al. BIOCHEMISTRY
- Piragliatin (RO4389620), a Novel Glucokinase Activator, Lowers Plasma Glucose Both in the Postabsorptive State and after a Glucose Challenge in Patients with Type 2 Diabetes Mellitus: A Mechanistic Study
- (2010) Riccardo C. Bonadonna et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Discovery, Structure−Activity Relationships, Pharmacokinetics, and Efficacy of Glucokinase Activator (2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675)
- (2010) Nancy-Ellen Haynes et al. JOURNAL OF MEDICINAL CHEMISTRY
- Endogenous Activation of Glucokinase by 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase Is Glucose Dependent
- (2010) Sara Langer et al. MOLECULAR ENDOCRINOLOGY
- Binding Kinetics of Glucose and Allosteric Activators to Human Glucokinase Reveal Multiple Conformational States
- (2009) Mathias Antoine et al. BIOCHEMISTRY
- Extremes of Clinical and Enzymatic Phenotypes in Children With Hyperinsulinism Caused by Glucokinase Activating Mutations
- (2009) S. Sayed et al. DIABETES
- Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia
- (2009) Kara K. Osbak et al. HUMAN MUTATION
- Assessing the potential of glucokinase activators in diabetes therapy
- (2009) Franz M. Matschinsky NATURE REVIEWS DRUG DISCOVERY
- Sugar binding to recombinant wild-type and mutant glucokinase monitored by kinetic measurement and tryptophan fluorescence
- (2008) Bogumil Zelent et al. BIOCHEMICAL JOURNAL
- Glucokinase and molecular aspects of liver glycogen metabolism
- (2008) Loranne Agius BIOCHEMICAL JOURNAL
- Glucose Modulation of Glucokinase Activation by Small Molecules†
- (2008) Erik C. Ralph et al. BIOCHEMISTRY
- Molecular Physiology of Mammalian Glucokinase
- (2008) P. B. Iynedjian CELLULAR AND MOLECULAR LIFE SCIENCES
- Catalytic activation of human glucokinase by substrate binding - residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions
- (2008) Janne Molnes et al. FEBS Journal
- Biophysical Characterization of the Interaction between Hepatic Glucokinase and Its Regulatory Protein
- (2008) Oliver Anderka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dual role of proapoptotic BAD in insulin secretion and beta cell survival
- (2008) Nika N Danial et al. NATURE MEDICINE
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