Current understanding of fatty acid biosynthesis and the acyl carrier protein

Solution Structure of an Acyl Carrier Protein Domain from a Fungal Type I Polyketide Synthase,

(2010) Pakorn Wattana-amorn et al.   BIOCHEMISTRY

Molecular Dynamics Simulations of β-Ketoacyl-, β-Hydroxyacyl-, andtrans-2-Enoyl-Acyl Carrier Proteins ofEscherichia coli

(2010) David I. Chan et al.   BIOCHEMISTRY

A Novel Role of Malonyl-ACP in Lipid Homeostasis,

(2010) Mariano A. Martinez et al.   BIOCHEMISTRY

Intein-mediated Cyclization of Bacterial Acyl Carrier Protein Stabilizes Its Folded Conformation but Does Not Abolish Function

(2010) Gerrit Volkmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Human Fatty Acid Synthase KS–MAT Didomain as a Framework for Inhibitor Design

(2010) Günter Pappenberger et al.   JOURNAL OF MOLECULAR BIOLOGY

Building Macromolecular Assemblies by Information-driven Docking

(2010) Ezgi Karaca et al.   MOLECULAR & CELLULAR PROTEOMICS

Production and secretion of fatty acids in genetically engineered cyanobacteria

(2010) X. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy

(2010) P. Gipson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amide exchange rates in Escherichia coli acyl carrier protein: Correlation with protein structure and dynamics

(2010) Michael Andrec et al.   PROTEIN SCIENCE

Structure and Malonyl CoA-ACP Transacylase Binding ofStreptomyces coelicolorFatty Acid Synthase Acyl Carrier Protein

(2009) Christopher J. Arthur et al.   ACS Chemical Biology

The Length of the Bound Fatty Acid Influences the Dynamics of the Acyl Carrier Protein and the Stability of the Thioester Bond

(2009) Gregory A. Zornetzer et al.   BIOCHEMISTRY

1H, 15N, 13C resonance assignment of the acyl carrier protein subunit of the Saccharomyces cerevisiae fatty acid synthase

(2009) Daniel R. Perez et al.   Biomolecular NMR Assignments

Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis

(2009) Lei Zhu et al.   BMC MICROBIOLOGY

Structural Basis for Different Specificities of Acyltransferases Associated with the Human Cytosolic and Mitochondrial Fatty Acid Synthases

(2009) Gabor Bunkoczi et al.   CHEMISTRY & BIOLOGY

Structural Insights into the Acyl Intermediates of thePlasmodium falciparumFatty Acid Synthesis Pathway

(2009) Santosh Kumar Upadhyay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of Mitochondrial Acyl Carrier Protein in Mammalian Cells Compromises Protein Lipoylation and Respiratory Complex I and Results in Cell Death

(2009) Dejiang Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acyl-Acyl Carrier Protein Regulates Transcription of Fatty Acid Biosynthetic Genes via the FabT Repressor inStreptococcus pneumoniae

(2009) Agoston Jerga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Escherichia coli Unsaturated Fatty Acid Synthesis

(2009) Youjun Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Regulation of Membrane Lipid Homeostasis in Escherichia coli

(2009) Kun Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Catalysis and mechanism of malonyl transferase activity in type II fatty acid biosynthesis acyl carrier proteins

(2009) Ashish Misra et al.   Molecular BioSystems

Structural insights into nonribosomal peptide enzymatic assembly lines

(2009) Alexander Koglin et al.   NATURAL PRODUCT REPORTS

Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

(2009) Sophie Brinster et al.   NATURE

Conformational flexibility of metazoan fatty acid synthase enables catalysis

(2009) Edward J Brignole et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural plasticity and catalysis regulation of a thermosensor histidine kinase

(2009) D. Albanesi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial fatty acid synthesis – An adopted set of enzymes making a pathway of major importance for the cellular metabolism

(2009) J. Kalervo Hiltunen et al.   PROGRESS IN LIPID RESEARCH

Tryptophan fluorescence reveals induced folding of Vibrio harveyi acyl carrier protein upon interaction with partner enzymes

(2008) Huansheng Gong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein

(2008) Simon E. Evans et al.   CHEMBIOCHEM

Covalent Linkage Mediates Communication between ACP and TE Domains in Modular Polyketide Synthases

(2008) Lucky Tran et al.   CHEMBIOCHEM

Protein–Protein Interactions in Multienzyme Megasynthetases

(2008) Kira J. Weissman et al.   CHEMBIOCHEM

Platensimycin: A Promising Antimicrobial Targeting Fatty Acid Synthesis

(2008) D. Manallack et al.   CURRENT MEDICINAL CHEMISTRY

The multienzyme architecture of eukaryotic fatty acid synthases

(2008) Marc Leibundgut et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Recent Progress and Future Directions in Protein-Protein Docking

(2008) David Ritchie   CURRENT PROTEIN & PEPTIDE SCIENCE

Role of DptE and DptF in the lipidation reaction of daptomycin

(2008) Melanie Wittmann et al.   FEBS Journal

Bacteria Possessing Two RelA/SpoT-Like Proteins Have Evolved a Specific Stringent Response Involving the Acyl Carrier Protein-SpoT Interaction

(2008) A. Battesti et al.   JOURNAL OF BACTERIOLOGY

Molecular Dynamics Simulations of the Apo-, Holo-, and Acyl-forms ofEscherichia coliAcyl Carrier Protein

(2008) David I. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Fatty Acid Synthesis Type II: More than Just Fatty Acids

(2008) J. Kalervo Hiltunen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanical Features ofPlasmodium falciparumAcyl Carrier Protein in the Delivery of Substrates

(2008) Francesco Colizzi et al.   Journal of Chemical Information and Modeling

Structural Enzymological Studies of 2-Enoyl Thioester Reductase of the Human Mitochondrial FAS II Pathway: New Insights into Its Substrate Recognition Properties

(2008) Zhi-Jun Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

Intersection of RNA Processing and the Type II Fatty Acid Synthesis Pathway in Yeast Mitochondria

(2008) M. S. Schonauer et al.   MOLECULAR AND CELLULAR BIOLOGY

Mitochondrial fatty acid synthesis is required for normal mitochondrial morphology and function in Trypanosoma brucei

(2008) Jennifer L. Guler et al.   MOLECULAR MICROBIOLOGY

Membrane lipid homeostasis in bacteria

(2008) Yong-Mei Zhang et al.   NATURE REVIEWS MICROBIOLOGY

Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli

(2008) W. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of the fungal fatty acid synthase type I multienzyme complex

(2008) P. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Crystal Structure of a Mammalian Fatty Acid Synthase

(2008) T. Maier et al.   SCIENCE

An Enzyme Assembly Line

(2008) J. L. Smith et al.   SCIENCE

An ancient genetic link between vertebrate mitochondrial fatty acid synthesis and RNA processing

(2007) Kaija J. Autio et al.   FASEB JOURNAL