Resistance of Dynamin-related Protein 1 Oligomers to Disassembly Impairs Mitophagy, Resulting in Myocardial Inflammation and Heart Failure

Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts

(2015) Moshi Song et al.   Cell Metabolism

Gone Fission...: Diverse Consequences of Cardiac Drp1 Deficiency

(2015) G. W. Dorn   CIRCULATION RESEARCH

Matrix Revisited

(2014) Andrew N. Carley et al.   CIRCULATION RESEARCH

Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

(2014) Yusuke Kageyama et al.   EMBO JOURNAL

Toll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA2

(2014) Y. Shintani et al.   EMBO REPORTS

A mutation associated with centronuclear myopathy enhances the size and stability of dynamin 2 complexes in cells

(2013) Nicholas G. James et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

New insights into the function and regulation of mitochondrial fission

(2013) Hidenori Otera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Genetic Cardiomyopathies Causing Heart Failure

(2013) Thomas J. Cahill et al.   CIRCULATION RESEARCH

Mitochondria: sensors and mediators of innate immune receptor signaling

(2013) Suzanne M Cloonan et al.   CURRENT OPINION IN MICROBIOLOGY

Mitochondrial Hyperfusion during Oxidative Stress Is Coupled to a Dysregulation in Calcium Handling within a C2C12 Cell Model

(2013) Calum J. Redpath et al.   PLoS One

Acute Inhibition of Excessive Mitochondrial Fission After Myocardial Infarction Prevents Long‐term Cardiac Dysfunction

(2013) Marie‐Hélène Disatnik et al.   Journal of the American Heart Association

Mitochondrial dynamics in heart disease

(2012) Gerald W. Dorn   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

(2012) Houman Ashrafian et al.   Cell Metabolism

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

Regulation of mitochondrial fission by intracellular Ca2+ in rat ventricular myocytes

(2010) Jennifer Hom et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

(2010) Sang-Bing Ong et al.   CIRCULATION

Dynamin 2 Mutants Linked to Centronuclear Myopathies Form Abnormally Stable Polymers

(2010) Lei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Lethalde NovoMutation in the Middle Domain of the Dynamin-related GTPase Drp1 Impairs Higher Order Assembly and Mitochondrial Division

(2010) Chuang-Rung Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

(2010) Paolo Grumati et al.   NATURE MEDICINE

A Mutation in the Mitochondrial Fission Gene Dnm1l Leads to Cardiomyopathy

(2010) Houman Ashrafian et al.   PLoS Genetics

Functional Significance and Morphological Characterization of Starvation-Induced Autophagy in the Adult Heart

(2009) Hiromitsu Kanamori et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial dynamics in heart cells: Very low amplitude high frequency fluctuations in adult cardiomyocytes and flow motion in non beating Hl-1 cells

(2009) Nathalie Beraud et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Controlling metabolism and cell death: At the heart of mitochondrial calcium signalling

(2009) Marta Murgia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

(2008) Philippe A. Parone et al.   PLoS One

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

(2008) G. M. Cereghetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

(2008) M. Saotome et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA