Identification of an Endogenously Generated Cryptic Collagen Epitope (XL313) That May Selectively Regulate Angiogenesis by an Integrin Yes-associated Protein (YAP) Mechano-transduction Pathway

Interaction of kindlin-2 with integrin  3 promotes outside-in signaling responses by the  V 3 vitronectin receptor

(2015) Z. Liao et al.   BLOOD

YAP Regulates S-Phase Entry in Endothelial Cells

(2015) Zhewei Shen et al.   PLoS One

Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo

(2014) Liangru W. Contois et al.   ANGIOGENESIS

Integrin αv in the mechanical response of osteoblast lineage cells

(2014) Keiko Kaneko et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Redefining the role(s) of endothelial αvβ3-integrin in angiogenesis: Figure 1

(2014) Samuel J. Atkinson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Production of Type VI Collagen by Human Macrophages: A New Dimension in Macrophage Functional Heterogeneity

(2014) M. Schnoor et al.   JOURNAL OF IMMUNOLOGY

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

(2014) Roger Stupp et al.   LANCET ONCOLOGY

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tissue-Infiltrating Neutrophils Constitute the Major In Vivo Source of Angiogenesis-Inducing MMP-9 in the Tumor Microenvironment

(2014) Elena I. Deryugina et al.   NEOPLASIA

Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src

(2013) Yan Gong et al.   ANGIOGENESIS

Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

(2013) Nadine Jetten et al.   ANGIOGENESIS

Acute Depletion of Endothelial β3-Integrin Transiently Inhibits Tumor Growth and Angiogenesis in Mice

(2013) Veronica Steri et al.   CIRCULATION RESEARCH

MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis

(2013) Yi Tang et al.   DEVELOPMENTAL CELL

Phosphorylation of Angiomotin by Lats1/2 Kinases Inhibits F-actin Binding, Cell Migration, and Angiogenesis

(2013) Xiaoming Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

M2-like macrophages are responsible for collagen degradation through a mannose receptor–mediated pathway

(2013) Daniel H. Madsen et al.   JOURNAL OF CELL BIOLOGY

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

(2013) Randy Johnson et al.   NATURE REVIEWS DRUG DISCOVERY

Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases

(2013) J. J. Adler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiangiogenic Therapies: Going beyond Their Limits

(2013) L. Moserle et al.   Cancer Discovery

Inside-out, outside-in, and inside–outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction

(2012) Bo Shen et al.   CURRENT OPINION IN CELL BIOLOGY

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

The role of β3-integrins in tumor angiogenesis: context is everything

(2011) Stephen D Robinson et al.   CURRENT OPINION IN CELL BIOLOGY

Insulin-like Growth Factor Binding Protein-4 Differentially Inhibits Growth Factor-induced Angiogenesis

(2011) Liangru W. Contois et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Early integrin binding to Arg-Gly-Asp peptide activates actin polymerization and contractile movement that stimulates outward translocation

(2011) C.-h. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Forty-Year Journey of Angiogenesis Translational Research

(2011) Y. Cao et al.   Science Translational Medicine

Macrophage-Mediated Proteolytic Remodeling of the Extracellular Matrix in Atherosclerosis Results in Neoepitopes: A Potential New Class of Biochemical Markers

(2010) Helene Skjøt-Arkil et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Pro-inflammatory angiogenesis is mediated by p38 MAP kinase

(2010) Gangaraju Rajashekhar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

G Protein Subunit G 13 Binds to Integrin  IIb 3 and Mediates Integrin "Outside-In" Signaling

(2010) H. Gong et al.   SCIENCE

Cooperation between integrin ανβ3 and VEGFR2 in angiogenesis

(2009) Payaningal R. Somanath et al.   ANGIOGENESIS

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors

(2009) Andrew R Reynolds et al.   NATURE MEDICINE

The Integrin Antagonist Cilengitide Activates αVβ3, Disrupts VE-Cadherin Localization at Cell Junctions and Enhances Permeability in Endothelial Cells

(2009) Gian Carlo Alghisi et al.   PLoS One

Integrins as “functional hubs” in the regulation of pathological angiogenesis

(2009) Liangru Contois et al.   SEMINARS IN CANCER BIOLOGY

Video monitoring of neovessel occlusion induced by photodynamic therapy with verteporfin (Visudyne®), in the CAM model

(2008) E. Debefve et al.   ANGIOGENESIS

αvβ3 integrin and angiogenesis: a moody integrin in a changing environment

(2008) Kairbaan Hodivala-Dilke   CURRENT OPINION IN CELL BIOLOGY

The angiogenic response is dictated by β3integrin on bone marrow–derived cells

(2008) Weiyi Feng et al.   JOURNAL OF CELL BIOLOGY

A role for VEGF as a negative regulator of pericyte function and vessel maturation

(2008) Joshua I. Greenberg et al.   NATURE

Fragments of extracellular matrix as mediators of inflammation

(2007) T ADAIRKIRK et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY