Syk Is Recruited to Stress Granules and Promotes Their Clearance through Autophagy

Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer

(2015) Mariya O. Krisenko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pathological stress granules in Alzheimer’s disease

(2014) Peter E.A. Ash et al.   BRAIN RESEARCH

STAT3-Mediated Autophagy Dependence Identifies Subtypes of Breast Cancer Where Autophagy Inhibition Can Be Efficacious

(2014) P. Maycotte et al.   CANCER RESEARCH

Syk Interacts with and Phosphorylates Nucleolin To Stabilize Bcl-xL mRNA and Promote Cell Survival

(2014) W.-H. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Getting Syk: spleen tyrosine kinase as a therapeutic target

(2014) Robert L. Geahlen   TRENDS IN PHARMACOLOGICAL SCIENCES

 2 integrin-derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis

(2013) T. Oellerich et al.   BLOOD

Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer

(2013) Akshata R Udyavar et al.   BMC Systems Biology

SYK Inhibition Modulates Distinct PI3K/AKT- Dependent Survival Pathways and Cholesterol Biosynthesis in Diffuse Large B Cell Lymphomas

(2013) Linfeng Chen et al.   CANCER CELL

Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

(2013) J. Ross Buchan et al.   CELL

SYK regulates mTOR signaling in AML

(2013) J Carnevale et al.   LEUKEMIA

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

(2012) Oliver D. King et al.   BRAIN RESEARCH

Autophagy and cancer

(2012) Kyeong Sook Choi   EXPERIMENTAL AND MOLECULAR MEDICINE

A novel retinoblastoma therapy from genomic and epigenetic analyses

(2012) Jinghui Zhang et al.   NATURE

Proteomic Profiling of a Mouse Model for Ovarian Granulosa Cell Tumor Identifies VCP as a Highly Sensitive Serum Tumor Marker in Several Human Cancers

(2012) Marie-Noëlle Laguë et al.   PLoS One

Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates

(2012) L. Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The dynamic nature of autophagy in cancer

(2011) A. C. Kimmelman   GENES & DEVELOPMENT

Proteomic Studies of Syk-Interacting Proteins Using a Novel Amine-Specific Isotope Tag and GFP Nanotrap

(2011) Jacob A. Galan et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Two Closely Spaced Tyrosines Regulate NFAT Signaling in B Cells via Syk Association with Vav

(2011) C.-H. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Alternative splicing of SYK regulates mitosis and cell survival

(2011) Panagiotis Prinos et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

TDP-43 and FUS: a nuclear affair

(2011) Dorothee Dormann et al.   TRENDS IN NEUROSCIENCES

In-depth Analyses of Kinase-dependent Tyrosine Phosphoproteomes Based on Metal Ion-functionalized Soluble Nanopolymers

(2010) Anton B. Iliuk et al.   MOLECULAR & CELLULAR PROTEOMICS

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

(2010) Janel O. Johnson et al.   NEURON

STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress

(2010) F. M. Uckun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Syk and pTyr'd: Signaling through the B cell antigen receptor

(2009) Robert L. Geahlen   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival

(2009) Anurag Singh et al.   CANCER CELL

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCδ and proteasome-dependent regulation of Mcl-1 expression

(2009) A D Baudot et al.   ONCOGENE

The protein-tyrosine kinase Syk interacts with TRAF-interacting protein TRIP in breast epithelial cells

(2009) Q Zhou et al.   ONCOGENE

Regulation of stress granule dynamics by Grb7 and FAK signalling pathway

(2008) Nien-Pei Tsai et al.   EMBO JOURNAL

Inhibition of ZAP-70 Kinase Activity via an Analog-sensitive Allele Blocks T Cell Receptor and CD28 Superagonist Signaling

(2008) Susan E. Levin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES