The BH4 Domain of Anti-apoptotic Bcl-XL, but Not That of the Related Bcl-2, Limits the Voltage-dependent Anion Channel 1 (VDAC1)-mediated Transfer of Pro-apoptotic Ca2+Signals to Mitochondria

Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival

(2014) Hristina Ivanova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

At the right distance: ER-mitochondria juxtaposition in cell life and death

(2014) Deborah Naon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Nucleotide Interactions of the Human Voltage-dependent Anion Channel

(2014) Saskia Villinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2+ uptake and reactive oxygen species generation

(2014) H Huang et al.   Cell Death & Disease

Bcl-2 family in inter-organelle modulation of calcium signaling; roles in bioenergetics and cell survival

(2013) Abasha Lewis et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

An Interaction between Bcl-xLand the Voltage-dependent Anion Channel (VDAC) Promotes Mitochondrial Ca2+Uptake

(2013) Huiya Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-terminal helix of Bcl-xL targets mitochondria

(2013) Melanie A. McNally et al.   MITOCHONDRION

Profiling of the Bcl-2/Bcl-XL-binding sites on type 1 IP3 receptor

(2012) Giovanni Monaco et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)

(2012) Arun Raturi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond

(2012) Giovanni Monaco et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mitochondrial VDAC1: Function in Cell Life and Death and a Target for Cancer Therapy

(2012) V. Shoshan-Barmatz et al.   CURRENT MEDICINAL CHEMISTRY

Mediation of the Antiapoptotic Activity of Bcl-xL Protein upon Interaction with VDAC1 Protein

(2012) Nir Arbel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis

(2012) Colins O. Eno et al.   MOLECULAR BIOLOGY OF THE CELL

To the knowledge of the 20GYGFG24 sequence stretch of type-1 VDAC: To understand why BCl-XL B4 domain peptides keep HeLa cells closed in hypotonic surroundings

(2012) Friedrich P. Thinnes   MOLECULAR GENETICS AND METABOLISM

Mitochondria as sensors and regulators of calcium signalling

(2012) Rosario Rizzuto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Flexibility of the N-Terminal mVDAC1 Segment Controls the Channel’s Gating Behavior

(2012) Barbara Mertins et al.   PLoS One

β-Barrel Mobility Underlies Closure of the Voltage-Dependent Anion Channel

(2012) Ulrich Zachariae et al.   STRUCTURE

VDAC proteomics: Post-translation modifications

(2011) Janos Kerner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Bcl-2 interaction with the inositol 1,4,5-trisphosphate receptor: Role in Ca2+ signaling and disease

(2011) Clark W. Distelhorst et al.   CELL CALCIUM

Calcium signaling around Mitochondria Associated Membranes (MAMs)

(2011) Simone Patergnani et al.   Cell Communication and Signaling

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl

(2011) G Monaco et al.   CELL DEATH AND DIFFERENTIATION

VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria

(2011) D De Stefani et al.   CELL DEATH AND DIFFERENTIATION

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Bcl-xL Blocks a Mitochondrial Inner Membrane Channel and Prevents Ca2+ Overload-Mediated Cell Death

(2011) Daniel Tornero et al.   PLoS One

Voltage-dependent anion channel involved in the mitochondrial calcium cycle of cell lines carrying the mitochondrial DNA A4263G mutation

(2010) Yuqi Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The IP3 receptor–mitochondria connection in apoptosis and autophagy

(2010) Jean-Paul Decuypere et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

l-β-ODAP alters mitochondrial Ca2+ handling as an early event in excitotoxicity

(2010) Marijke Van Moorhem et al.   CELL CALCIUM

Apoptosis Protection by Mcl-1 and Bcl-2 Modulation of Inositol 1,4,5-Trisphosphate Receptor-dependent Ca2+Signaling

(2010) Emily F. Eckenrode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VDAC, a multi-functional mitochondrial protein regulating cell life and death

(2010) Varda Shoshan-Barmatz et al.   MOLECULAR ASPECTS OF MEDICINE

Apoptosis and Autophagy: Decoding Calcium Signals that Mediate Life or Death

(2010) M. W. Harr et al.   Cold Spring Harbor Perspectives in Biology

Structural and functional link between the mitochondrial network and the endoplasmic reticulum

(2009) Carlotta Giorgi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Voltage-dependent Anion Channel 1-based Peptides Interact with Bcl-2 to Prevent Antiapoptotic Activity

(2009) Nir Arbel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins

(2009) S. Abu-Hamad et al.   JOURNAL OF CELL SCIENCE

Sigma-1 Receptors Regulate Bcl-2 Expression by Reactive Oxygen Species-Dependent Transcriptional Regulation of Nuclear Factor  B

(2009) J. Meunier et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

(2009) Y.-P. Rong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model

(2008) E Decrock et al.   CELL DEATH AND DIFFERENTIATION

Regulation of Bcl-2 Family Proteins by Posttranslational Modifications

(2008) Anthony Letai et al.   CURRENT MOLECULAR MEDICINE

Voltage-dependent anion channel 1 is involved in endostatin-induced endothelial cell apoptosis

(2008) Shaopeng Yuan et al.   FASEB JOURNAL

Uncovering the role of VDAC in the regulation of cell life and death

(2008) Varda Shoshan-Barmatz et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Voltage-dependent Anion Channel 1-based Peptides Interact with Hexokinase to Prevent Its Anti-apoptotic Activity

(2008) Laetitia Arzoine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Bcl-2-IP3 Receptor Interaction to Reverse Bcl-2's Inhibition of Apoptotic Calcium Signals

(2008) Yi-Ping Rong et al.   MOLECULAR CELL

Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death

(2008) N Tajeddine et al.   ONCOGENE

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE

Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles

(2008) S. Hiller et al.   SCIENCE