Analysis of Cytochrome P450 CYP119 Ligand-dependent Conformational Dynamics by Two-dimensional NMR and X-ray Crystallography

Human Cytochrome P450 17A1 Conformational Selection

(2014) D. Fernando Estrada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytochrome P450 Bioreactors in the Pharmaceutical Industry: Challenges and Opportunities

(2013) Carlos Martinez et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Polyaromatic hydrocarbon exposure: an ecological impact ambiguity

(2013) Andrew Ball et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

A Model of the Membrane-bound Cytochromeb5-Cytochrome P450 Complex from NMR and Mutagenesis Data

(2013) Shivani Ahuja et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate-modulated Cytochrome P450 17A1 and Cytochromeb5Interactions Revealed by NMR

(2013) D. Fernando Estrada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Interaction Between Membrane-Bound Full-Length Cytochrome P450 and Cytochrome b5 Observed by Solid-State NMR Spectroscopy

(2013) Kazutoshi Yamamoto et al.   Scientific Reports

Solution Structural Ensembles of Substrate-Free Cytochrome P450cam

(2012) Eliana K. Asciutto et al.   BIOCHEMISTRY

Double electron-electron resonance shows cytochrome P450cam undergoes a conformational change in solution upon binding substrate

(2012) S. Stoll et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Active-site residues move independently from the rest of the protein in a 200ns molecular dynamics simulation of cytochrome P450 CYP119

(2011) Relly Brandman et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Accessing protein conformational ensembles using room-temperature X-ray crystallography

(2011) J. S. Fraser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temperature-dependent macromolecular X-ray crystallography

(2010) Martin Weik et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Comparison of NMR and crystal structures for the proteins TM1112 and TM1367

(2010) Biswaranjan Mohanty et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Comparison of NMR and crystal structures highlights conformational isomerism in protein active sites

(2010) Pedro Serrano et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

NMR structure of the protein NP_247299.1: comparison with the crystal structure

(2010) Kristaps Jaudzems et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Three Clusters of Conformational States in P450cam Reveal a Multistep Pathway for Closing of the Substrate Access Channel,

(2010) Young-Tae Lee et al.   BIOCHEMISTRY

Two-dimensional NMR and All-atom Molecular Dynamics of Cytochrome P450 CYP119 Reveal Hidden Conformational Substates

(2010) Jed N. Lampe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calculated and Experimental Spin State of Seleno Cytochrome P450

(2009) Yongying Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Induced Conformational Heterogeneity of Cytochrome P450 CYP119 Identified by 2D NMR Spectroscopy with the Unnatural Amino Acid13C-p-Methoxyphenylalanine

(2008) Jed N. Lampe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structures of invisible, excited protein states by relaxation dispersion NMR spectroscopy

(2008) P. Vallurupalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA