Glutathionylation of the Active Site Cysteines of Peroxiredoxin 2 and Recycling by Glutaredoxin

A primer on peroxiredoxin biochemistry

(2015) P. Andrew Karplus   FREE RADICAL BIOLOGY AND MEDICINE

Redox Proteomics of the Inflammatory Secretome Identifies a Common Set of Redoxins and Other Glutathionylated Proteins Released in Inflammation, Influenza Virus Infection and Oxidative Stress

(2015) Paola Checconi et al.   PLoS One

Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling

(2014) Mirko C Sobotta et al.   Nature Chemical Biology

Signaling via a peroxiredoxin sensor

(2014) Christine C Winterbourn et al.   Nature Chemical Biology

Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal

(2014) S. Salzano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen peroxide sensing, signaling and regulation of transcription factors

(2014) H. Susana Marinho et al.   Redox Biology

Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling

(2013) Eva-Maria Hanschmann et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutaredoxin 2 Reduces Both Thioredoxin 2 and Thioredoxin 1 and Protects Cells from Apoptosis Induced by Auranofin and 4-Hydroxynonenal

(2013) Huihui Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Hyperoxidized peroxiredoxin 2 interacts with the protein disulfide- isomerase ERp46

(2013) Paul E. Pace et al.   BIOCHEMICAL JOURNAL

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hyperoxidation of Peroxiredoxins 2 and 3

(2013) Alexander V. Peskin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxiredoxin 1 functions as a signal peroxidase to receive, transduce, and transmit peroxide signals in mammalian cells

(2012) Reagan M. Jarvis et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glutathione and Glutaredoxin Act as a Backup of Human Thioredoxin Reductase 1 to Reduce Thioredoxin 1 Preventing Cell Death by Aurothioglucose

(2012) Yatao Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Posttranslational Modification of Cysteine in Redox Signaling and Oxidative Stress: Focus on S-Glutathionylation

(2011) John J. Mieyal et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutathionylation of Peroxiredoxin I Induces Decamer to Dimers Dissociation with Concomitant Loss of Chaperone Activity

(2011) Ji Won Park et al.   BIOCHEMISTRY

Multiple Functions of Peroxiredoxins: Peroxidases, Sensors and Regulators of the Intracellular Messenger H2O2, and Protein Chaperones

(2010) Sue Goo Rhee et al.   ANTIOXIDANTS & REDOX SIGNALING

Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum

(2010) Timothy J Tavender et al.   EMBO JOURNAL

Both Thioredoxin 2 and Glutaredoxin 2 Contribute to the Reduction of the Mitochondrial 2-Cys Peroxiredoxin Prx3

(2010) Eva-Maria Hanschmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of the peroxiredoxin family: Using active-site structure and sequence information for global classification and residue analysis

(2010) Kimberly J. Nelson et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Typical 2-Cys peroxiredoxins - structures, mechanisms and functions

(2009) Andrea Hall et al.   FEBS Journal

Deglutathionylation of 2-Cys Peroxiredoxin Is Specifically Catalyzed by Sulfiredoxin

(2009) Ji Won Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Protective Mechanism against Irreversible Hyperoxidation of Peroxiredoxin

(2009) Jae Ho Seo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Simultaneous determination of reduced glutathione, glutathione disulphide and glutathione sulphonamide in cells and physiological fluids by isotope dilution liquid chromatography–tandem mass spectrometry

(2009) D. Tim Harwood et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2

(2008) Bruno Manta et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Thiol chemistry and specificity in redox signaling

(2008) Christine C. Winterbourn et al.   FREE RADICAL BIOLOGY AND MEDICINE