TGFβ-activated Kinase 1 (TAK1) Inhibition by 5Z-7-Oxozeaenol Attenuates Early Brain Injury after Experimental Subarachnoid Hemorrhage

Involvement of neuronal TGF-β activated kinase 1 in the development of tolerance to morphine-induced antinociception in rat spinal cord

(2015) Hao Xu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model

(2015) D. J. Ireland et al.   MOLECULAR HUMAN REPRODUCTION

Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling

(2015) Patty C.H. Cai et al.   Oncotarget

The rodent endovascular puncture model of subarachnoid hemorrhage: mechanisms of brain damage and therapeutic strategies

(2014) Elke Kooijman et al.   Journal of Neuroinflammation

CPEB Regulation of TAK1 Synthesis Mediates Cytokine Production and the Inflammatory Immune Response

(2014) Maria Ivshina et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular Basis of NF-κB Signaling

(2013) Johanna Napetschnig et al.   Annual Review of Biophysics

Expression and cell distribution of myeloid differentiation primary response protein 88 in the cerebral cortex following experimental subarachnoid hemorrhage in rats: A pilot study

(2013) Qing Sun et al.   BRAIN RESEARCH

Genetic Elimination of eNOS Reduces Secondary Complications of Experimental Subarachnoid Hemorrhage

(2013) Mohammed Sabri et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The role of microglia and the TLR4 pathway in neuronal apoptosis and vasospasm after subarachnoid hemorrhage

(2013) Khalid A Hanafy   Journal of Neuroinflammation

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

P2X7R/cryopyrin inflammasome axis inhibition reduces neuroinflammation after SAH

(2013) Sheng Chen et al.   NEUROBIOLOGY OF DISEASE

Isoflurane on brain inflammation

(2013) Orhan Altay et al.   NEUROBIOLOGY OF DISEASE

Inhibition of transforming growth factor beta-activated kinase 1 confers neuroprotection after traumatic brain injury in rats

(2013) D. Zhang et al.   NEUROSCIENCE

Activation of Nuclear Factor-κB in the Brain after Experimental Subarachnoid Hemorrhage and Its Potential Role in Delayed Brain Injury

(2013) Wan-Chun You et al.   PLoS One

Cell type-specific function of TAK1 in innate immune signaling

(2013) Adebusola A. Ajibade et al.   TRENDS IN IMMUNOLOGY

Early Brain Injury, an Evolving Frontier in Subarachnoid Hemorrhage Research

(2013) Mutsumi Fujii et al.   Translational Stroke Research

Mechanism and In Vitro Pharmacology of TAK1 Inhibition by (5Z)-7-Oxozeaenol

(2012) Jiaquan Wu et al.   ACS Chemical Biology

Protection from cerebral ischemia by inhibition of TGFβ-activated kinase

(2012) Benjamin J. White et al.   EXPERIMENTAL NEUROLOGY

TAK1 inhibition for treatment of cerebral ischemia

(2012) Dirk A. Ridder et al.   EXPERIMENTAL NEUROLOGY

TAK1 Negatively Regulates NF-κB and p38 MAP Kinase Activation in Gr-1+CD11b+ Neutrophils

(2012) Adebusola Alagbala Ajibade et al.   IMMUNITY

Transition of research focus from vasospasm to early brain injury after subarachnoid hemorrhage

(2012) Basak Caner et al.   JOURNAL OF NEUROCHEMISTRY

Melatonin activates the Nrf2-ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage model

(2012) Zhong Wang et al.   JOURNAL OF PINEAL RESEARCH

Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats

(2012) Mutsumi Fujii et al.   NEUROCHEMISTRY INTERNATIONAL

Expression of NR2B in different brain regions and effect of NR2B antagonism on learning deficits after experimental subarachnoid hemorrhage

(2012) G. Chen et al.   NEUROSCIENCE

The importance of early brain injury after subarachnoid hemorrhage

(2012) Fatima A. Sehba et al.   PROGRESS IN NEUROBIOLOGY

Targeting of TAK1 in inflammatory disorders and cancer

(2012) Hiroaki Sakurai   TRENDS IN PHARMACOLOGICAL SCIENCES

Acute inhibition of TAK1 protects against neuronal death in cerebral ischemia

(2011) M Neubert et al.   CELL DEATH AND DIFFERENTIATION

Progesterone Administration Modulates Cortical TLR4/NF-κB Signaling Pathway after Subarachnoid Hemorrhage in Male Rats

(2011) Zhong Wang et al.   MEDIATORS OF INFLAMMATION

Learning deficits after experimental subarachnoid hemorrhage in rats

(2010) H. Jeon et al.   NEUROSCIENCE

Inflammation and brain injury: Acute cerebral ischaemia, peripheral and central inflammation

(2009) A. Denes et al.   BRAIN BEHAVIOR AND IMMUNITY

Role of Interleukin-1β in Early Brain Injury After Subarachnoid Hemorrhage in Mice

(2009) Takumi Sozen et al.   STROKE

Neuronal and astrocytic apoptosis after subarachnoid hemorrhage: A possible cause for poor prognosis

(2008) Mohammed Sabri et al.   BRAIN RESEARCH

Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop Is Required for Interleukin (IL)-1-mediated Optimal NFκB and AP-1 Activation as Well as IL-6 Gene Expression

(2008) Yang Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High CSF transforming growth factor   levels after subarachnoid haemorrhage: association with chronic communicating hydrocephalus

(2008) M R Douglas et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY