Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (bpV(phen)) Induces Apoptosis and Pyroptosis and Disrupts the P62-HDAC6 Protein Interaction to Suppress the Acetylated Microtubule-dependent Degradation of Autophagosomes

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Protein Tyrosine Phosphatases Regulate Asthma Development in a Murine Asthma Model

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Autophagy Inhibitor LRPPRC Suppresses Mitophagy through Interaction with Mitophagy Initiator Parkin

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Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy

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Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability

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SQSTM1/p62 Interacts with HDAC6 and Regulates Deacetylase Activity

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Inflammasomes and Their Roles in Health and Disease

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MAP1S enhances autophagy to suppress tumorigenesis

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Autophagy Suppresses Interleukin-1β (IL-1β) Signaling by Activation of p62 Degradation via Lysosomal and Proteasomal Pathways

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Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

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Acetylated microtubules are required for fusion of autophagosomes with lysosomes

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Control of infection by pyroptosis and autophagy: role of TLR and NLR

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PTEN inhibitors cause a negative inotropic and chronotropic effect in mice

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A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Protein tyrosine phosphatase inhibition induces anti-tumor activity: Evidence of Cdk2/p27kip1 and Cdk2/SHP-1 complex formation in human ovarian cancer cells

(2008) Danielle Caron et al.   CANCER LETTERS

Autophagy in the Pathogenesis of Disease

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Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY