The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053

Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis

(2014) David Albesa-Jové et al.   ACS Chemical Biology

2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1

(2014) João Neres et al.   ACS Chemical Biology

Tuberculosis drug discovery in the post-post-genomic era

(2014) Benoit Lechartier et al.   EMBO Molecular Medicine

Protein disulfide isomerase a multifunctional protein with multiple physiological roles

(2014) Hyder Ali Khan et al.   Frontiers in Chemistry

Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling

(2013) Eva-Maria Hanschmann et al.   ANTIOXIDANTS & REDOX SIGNALING

Progress in targeting cell envelope biogenesis inMycobacterium tuberculosis

(2013) Mary Jackson et al.   Future Microbiology

Conformational Plasticity of the Essential Membrane-associated Mannosyltransferase PimA from Mycobacteria

(2013) David Giganti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Crowding Stabilizes Both the Intrinsically Disordered Calcium-Free State and the Folded Calcium-Bound State of a Repeat in Toxin (RTX) Protein

(2013) Ana-Cristina Sotomayor-Pérez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Advances in the development of new tuberculosis drugs and treatment regimens

(2013) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

Tuberculosis

(2013) Alimuddin Zumla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Approval of Novel TB Drug Celebrated--With Restraint

(2013) J. Cohen   SCIENCE

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Small-Angle X-Ray Scattering on Biological Macromolecules and Nanocomposites in Solution

(2012) Clement E. Blanchet et al.   Annual Review of Physical Chemistry

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid

(2012) Ruben C. Hartkoorn et al.   EMBO Molecular Medicine

Human cytosolic glutathione transferases: structure, function, and drug discovery

(2012) Baojian Wu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The helix bundle: A reversible lipid binding motif

(2009) Vasanthy Narayanaswami et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

DAMMIF, a program for rapidab-initioshape determination in small-angle scattering

(2009) Daniel Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Preparation and structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB

(2008) Goran Malojčić et al.   FEBS LETTERS

The Catalytic Activity of Protein-disulfide Isomerase Requires a Conformationally Flexible Molecule

(2008) Geng Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and mechanisms of the DsbB–DsbA disulfide bond generation machine

(2007) Kenji Inaba et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH