期刊
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY
卷 27, 期 3, 页码 415-431出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.bpg.2013.06.009
关键词
Extraoesophageal reflux syndrome; Chronic laryngitis; Asthma; Chronic cough; Reflux
Reflux related cough, asthma and laryngitis are frequently encountered and are considered part of extraoesophageal syndromes. The diagnosis of extraoesophageal reflux is difficult due to the lack of gold standard diagnostic criteria. Esophagogastroduodenoscopy and esophageal pH monitoring are inadequate diagnostic tools for due to poor sensitivity and specificity. For this reason, empirical PPI therapy is recommended as an initial approach to diagnose and treat the potential underlying cause of these symptoms in patients without alarm symptoms. Diagnostic testing with esophageal pH and/or impedance monitoring and esophageal motility testing is usually reserved for those who continue to be symptomatic despite a trial of therapy with PPIs. Recent developments have increased our understanding of this difficult to treat group of patients but more research into reflux related extraoesophageal symptoms are needed to better diagnose and treat this group. (c) 2013 Elsevier Ltd. All rights reserved.
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