O-Linked β-N-acetylglucosamine (O-GlcNAc) Acts as a Glucose Sensor to Epigenetically Regulate the Insulin Gene in Pancreatic Beta Cells

Intracellular protein glycosylation modulates insulin mediated lifespan in C. elegans

(2016) Mohammad M. Rahman et al.   Aging-US

O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41

(2014) Stéphanie Olivier-Van Stichelen et al.   FASEB JOURNAL

DecreasedO-Linked GlcNAcylation Protects from Cytotoxicity Mediated by Huntingtin Exon1 Protein Fragment

(2014) Amit Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis

(2013) Jennifer A. Groves et al.   CELL STRESS & CHAPERONES

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

(2013) Rachel Deplus et al.   EMBO JOURNAL

TET3-OGT interaction increases the stability and the presence of OGT in chromatin

(2013) Ryo Ito et al.   GENES TO CELLS

Epigenetic Switching by the Metabolism-sensing Factors in the Generation of Orexin Neurons from Mouse Embryonic Stem Cells

(2013) Koji Hayakawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-Linked β-N-Acetylglucosamine (O-GlcNAc) Site Thr-87 Regulates Synapsin I Localization to Synapses and Size of the Reserve Pool of Synaptic Vesicles

(2013) Yuliya Skorobogatko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Roles of IRF-3 and IRF-7 in Innate Antiviral Immunity against Dengue Virus

(2013) H.-W. Chen et al.   JOURNAL OF IMMUNOLOGY

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

O-GlcNAc and the cardiovascular system

(2013) Sujith Dassanayaka et al.   PHARMACOLOGY & THERAPEUTICS

Activation of the Transcriptional Function of the NF- B Protein c-Rel by O-GlcNAc Glycosylation

(2013) P. Ramakrishnan et al.   Science Signaling

Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm

(2012) I. I. Muller et al.   Disease Models & Mechanisms

Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy

(2012) Volker Ruppert et al.   GENE

Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart

(2012) Susan A. Marsh et al.   LIFE SCIENCES

linking metabolism to epigenetics through O-GlcNAcylation

(2012) John A. Hanover et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases

(2012) P. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Regulation of Polymerase II Transcription Initiation in Trypanosoma cruzi: Modulation of Nucleosome Abundance, Histone Modification, and Polymerase Occupancy by O-Linked Thymine DNA Glucosylation

(2011) Dilrukshi Ekanayake et al.   EUKARYOTIC CELL

Pleiotropic and Age-dependent Effects of Decreased Protein Modification byO-LinkedN-Acetylglucosamine on Pancreatic β-Cell Function and Vascularization

(2011) Yudi Soesanto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport

(2011) Kazuaki Ohtsubo et al.   NATURE MEDICINE

From RNA-seq reads to differential expression results

(2011) Alicia Oshlack et al.   GENOME BIOLOGY

Modulation of transcription factor function by O-GlcNAc modification

(2010) Sabire Özcan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Upregulation of stress-response genes with cell cycle arrest induced by carbon ion irradiation in multiple murine tumors models

(2010) Kaori Imadome et al.   CANCER BIOLOGY & THERAPY

Genome-wide analysis of histone modifications in human pancreatic islets

(2010) R. Bhandare et al.   GENOME RESEARCH

O-GlcNAc Cycling Enzymes Associate with the Translational Machinery and Modify Core Ribosomal Proteins

(2010) Quira Zeidan et al.   MOLECULAR BIOLOGY OF THE CELL

 -N-acetylglucosamine (O-GlcNAc) is part of the histone code

(2010) K. Sakabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-GlcNAc cycling: Emerging roles in development and epigenetics

(2010) Dona C. Love et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death

(2009) Gladys A. Ngoh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways

(2009) Q. Zeidan et al.   JOURNAL OF CELL SCIENCE

Characterization of Schlafen-3 expression in effector and regulatory T cells

(2009) T. Condamine et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides

(2009) R. J. Chalkley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A PGC-1α-O-GlcNAc Transferase Complex Regulates FoxO Transcription Factor Activity in Response to Glucose

(2008) Michael P. Housley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-GlcNAc Regulates FoxO Activation in Response to Glucose

(2008) Michael P. Housley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The importance of RNA binding proteins in preproinsulin mRNA stability

(2008) R FRED et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

(2008) Takbum Ohn et al.   NATURE CELL BIOLOGY