期刊
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
卷 8, 期 -, 页码 1098-1104出版社
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.8.121
关键词
asymmetric [3+2] annulation; maleimides; Morita-Baylis-Hillman carbonates; multifunctional thiourea-phosphine; organocatalysis
资金
- Shanghai Municipal Committee of Science and Technology [11JC1402600]
- National Basic Research Program of China (973) [2010CB833302]
- National Natural Science Foundation of China [21072206, 20472096, 20872162, 20672127, 21121062, 20732008]
We have developed a multifunctional thiourea-phosphine catalyzed asymmetric [3 + 2] annulation of Morita-Baylis-Hillman (MBH) carbonates with maleimides, which can efficiently construct functionalized cyclopentenes bearing three contiguous stereocenters in moderate to excellent yields and excellent diastereo- and enantioselectivities. A plausible mechanism has been also proposed on the basis of control experiments and previous literature.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据