期刊
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
卷 8, 期 -, 页码 308-312出版社
BEILSTEIN-INSTITUT
DOI: 10.3762/bjoc.8.33
关键词
aldol reaction; fused-ring systems; heterocycles; isoxazole; metalation; pyridone
资金
- Open University
- Loughborough University
- Syngenta
A core 4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-one scaffold is elaborated at C-3( Me) by base-mediated aldol condensation to give new 3-alkenyl-4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-ones, which are masked forms related to the acylpyridone natural products.
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