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Animal models of neuropsychiatry revisited: A personal tribute to Teitelbaum

期刊

BEHAVIOURAL BRAIN RESEARCH
卷 231, 期 2, 页码 337-342

出版社

ELSEVIER
DOI: 10.1016/j.bbr.2012.03.005

关键词

Conditioning; Animal model; Endophenotype; Addiction

资金

  1. Medical Research Council Funding Source: Medline
  2. Wellcome Trust Funding Source: Medline

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Several themes and principles of behavioural neuroscience are evident in the work of Phillip Teitelbaum. He has emphasised the importance of studying behaviour in simple preparations, of re-synthesising complex behavioural patterns from these elemental 'building-blocks' and understanding their often hierarchical organisation. He also more recently has become interested in the possible power of behavioural endophenotypes. His work has resulted in a new emphasis on animal neuropsychology which is highly relevant to human psychopathology. This article illustrates these themes from examples taken from animal models of sensory neglect, drug addiction and cognitive syndromes associated with schizophrenia and other neuropsychiatric disorders. (C) 2012 Elsevier B.V. All rights reserved.

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