4.6 Article

Housing supplementation decreases the magnitude of inflammation-induced nociception in rats

期刊

BEHAVIOURAL BRAIN RESEARCH
卷 197, 期 1, 页码 230-233

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ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbr.2008.08.010

关键词

Environmental enrichment; Inflammation; Complete Freund's adjuvant; Hyperalgesia; Housing supplementation; Long-Evans rats

资金

  1. School of Graduate Studies and Research at Youngstown State University

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Previous reports have demonstrated that pain is influenced by environmental factors. This investigation examined the effects of housing supplementation, via the inclusion of objects to the home cage environment, on inflammation-induced nociceptive behaviors. The degree of thermal hyperalgesia was significantly lower in rats housed in a supplemented home cage environment, as compared to rats housed in basic cages. These data indicate that environmental enrichment significantly affects nociceptive responses. (c) 2008 Elsevier B.V. All rights reserved.

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