期刊
BEHAVIOR GENETICS
卷 45, 期 2, 页码 200-214出版社
SPRINGER
DOI: 10.1007/s10519-014-9698-y
关键词
Gene-environment interaction; SES; Multimodel inference; General cognitive ability; IQ; Twin study; Adoption study
资金
- USPHS Grants from the National Institute on Alcohol Abuse and Alcoholism [AA09367, AA11886]
- National Institute on Drug Abuse [DA05147, DA13240, DA024417]
- National Institute on Mental Health [MH066140, DA026119]
- University of Minnesota Graduate School
The present study of general cognitive ability attempts to replicate and extend previous investigations of a biometric moderator, family-of-origin socioeconomic status (SES), in a sample of 2,494 pairs of adolescent twins, non-twin biological siblings, and adoptive siblings assessed with individually administered IQ tests. We hypothesized that SES would covary positively with additive-genetic variance and negatively with shared-environmental variance. Important potential confounds unaddressed in some past studies, such as twin-specific effects, assortative mating, and differential heritability by trait level, were found to be negligible. In our main analysis, we compared models by their sample-size corrected AIC, and base our statistical inference on model-averaged point estimates and standard errors. Additive-genetic variance increased with SES-an effect that was statistically significant and robust to model specification. We found no evidence that SES moderated shared-environmental influence. We attempt to explain the inconsistent replication record of these effects, and provide suggestions for future research.
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