Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction

S100A8/A9 aggravates post-ischemic heart failure through activation of RAGE-dependent NF-κB signaling

(2012) H. Christian Volz et al.   BASIC RESEARCH IN CARDIOLOGY

Cardiomyogenesis in the Aging and Failing Human Heart

(2012) Jan Kajstura et al.   CIRCULATION

Role of TWEAK in lupus nephritis: A bench-to-bedside review

(2012) Jennifer S. Michaelson et al.   JOURNAL OF AUTOIMMUNITY

TWEAK/Fn14 promotes the proliferation and collagen synthesis of rat cardiac fibroblasts via the NF-кB pathway

(2012) Hui-Na Chen et al.   MOLECULAR BIOLOGY REPORTS

The TIR/BB-loop mimetic AS-1 prevents cardiac hypertrophy by inhibiting IL-1R-mediated MyD88-dependent signaling

(2011) Yun Zhu et al.   BASIC RESEARCH IN CARDIOLOGY

Recent Progress in the Management of Pulmonary Hypertension

(2011) Yoshihiro Fukumoto et al.   CIRCULATION JOURNAL

Soluble TWEAK predicts hemodynamic impairment and functional capacity in patients with pulmonary arterial hypertension

(2011) Arthur Filusch et al.   Clinical Research in Cardiology

The TWEAK-Fn14 System: Breaking the Silence of Cytokine-Induced Skeletal Muscle Wasting

(2011) S. Bhatnagar et al.   CURRENT MOLECULAR MEDICINE

When are pro-inflammatory cytokines SAFE in heart failure?

(2011) S. Lecour et al.   EUROPEAN HEART JOURNAL

TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses

(2011) Linda C. Burkly et al.   IMMUNOLOGICAL REVIEWS

Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats

(2010) E. Mustonen et al.   Acta Physiologica

Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction

(2010) Eric M. Small et al.   CIRCULATION RESEARCH

Association of Left Atrial Endothelin-1 With Atrial Rhythm, Size, and Fibrosis in Patients With Structural Heart Disease

(2010) Fadia Mayyas et al.   Circulation-Arrhythmia and Electrophysiology

The origin of fibroblasts and mechanism of cardiac fibrosis

(2010) Guido Krenning et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Direct targeting of fibroblast growth factor-inducible 14 protein protects against renal ischemia reperfusion injury

(2010) Kiyohiko Hotta et al.   KIDNEY INTERNATIONAL

TNFα in atherosclerosis, myocardial ischemia/reperfusion and heart failure

(2010) Petra Kleinbongard et al.   PHARMACOLOGY & THERAPEUTICS

FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK

(2009) Emmanuel Chorianopoulos et al.   BASIC RESEARCH IN CARDIOLOGY

Time course and mechanisms of left ventricular systolic and diastolic dysfunction in monocrotaline-induced pulmonary hypertension

(2009) Jorge Correia-Pinto et al.   BASIC RESEARCH IN CARDIOLOGY

TWEAK is a positive regulator of cardiomyocyte proliferation

(2009) Tatyana Novoyatleva et al.   CARDIOVASCULAR RESEARCH

The Right Ventricle Under Pressure

(2009) Harm J. Bogaard et al.   CHEST

A Novel Role for Tumor Necrosis Factor–Like Weak Inducer of Apoptosis (TWEAK) in the Development of Cardiac Dysfunction and Failure

(2009) Mohit Jain et al.   CIRCULATION

Soluble TWEAK Plasma Levels as a Novel Biomarker of Endothelial Function in Patients with Chronic Kidney Disease

(2009) M. I. Yilmaz et al.   Clinical Journal of the American Society of Nephrology

Negative Regulation of the EGFR-MAPK Cascade by Actin-MAL-Mediated Mig6/Errfi-1 Induction

(2009) Arnaud Descot et al.   MOLECULAR CELL

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis

(2009) Souhila Medjkane et al.   NATURE CELL BIOLOGY

The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting

(2008) Jeffrey A. Winkles   NATURE REVIEWS DRUG DISCOVERY