Article
Endocrinology & Metabolism
Chiara M. A. Cefalo, Alessia Riccio, Teresa Vanessa Fiorentino, Elena Succurro, Sofia Miceli, Gaia Chiara Mannino, Maria Perticone, Angela Sciacqua, Francesco Andreozzi, Giorgio Sesti
Summary: Metabolic syndrome and elevated hsCRP levels are associated with an impaired myocardial MEE, which is an independent predictor of cardiovascular diseases. Nondiabetic and prediabetic individuals with metabolic syndrome exhibit increased stroke work and myocardial oxygen consumption, and the combination of elevated hsCRP levels and metabolic syndrome aggravates the impairment of myocardial MEE.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Multidisciplinary Sciences
Lan Cheng, Qianyu Fu, Longhua Zhou, Yuqin Fan, Fenfen Liu, Yuanyuan Fan, Xin Zhang, Weiqing Lin, Xiaohe Wu
Summary: The study demonstrated that dapagliflozin combined with metformin is more effective in treating patients with metabolic syndrome compared to dapagliflozin or metformin monotherapy, with improvements in all components of metabolic syndrome.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Anton V. Tyurin, Milyausha K. Salimgareeva, Ildar R. Miniakhmetov, Rita I. Khusainova, Alexandr Samorodov, Valentin N. Pavlov, Julia Kzhyshkowska
Summary: The immune system is severely compromised in patients with COVID-19, showing correlations with inflammation levels and subsets of immune cells. Additionally, deficiencies in the adaptive immune system are correlated with deficiencies in iron metabolism.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Patrick R. Lawler, Deepak L. Bhatt, Lucas C. Godoy, Thomas F. Luscher, Robert O. Bonow, Subodh Verma, Paul M. Ridker
Summary: Systemic vascular inflammation plays crucial roles in the progression and destabilization of ASCVD, requiring more individualized approaches for successful clinical translation. High-sensitivity C-reactive protein may serve as a clinical measure of inflammation.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Hadas Ben-Assayag, Rafael Y. Brzezinski, Shlomo Berliner, David Zeltser, Itzhak Shapira, Ori Rogowski, Sharon Toker, Roy Eldor, Shani Shenhar-Tsarfaty
Summary: This study aimed to determine the prevalence of metabolically healthy individuals and characterize the transition from metabolic health to dysfunction. It found that roughly one-quarter of apparently healthy adults meet the current definitions of metabolic health. The transition from health to metabolic dysfunction is accompanied by inflammation and changes in several non-metabolic syndrome biomarkers. Aggressive screening for these biomarkers, blood pressure, and hsCRP might help identify apparently healthy individuals at increased risk of developing metabolic syndrome.
CARDIOVASCULAR DIABETOLOGY
(2023)
Review
Endocrinology & Metabolism
Florentina Duica, Cezara Alina Danila, Andreea Elena Boboc, Panagiotis Antoniadis, Carmen Elena Condrat, Sebastian Onciul, Nicolae Suciu, Sanda Maria Cretoiu, Valentin Nicolae Varlas, Dragos Cretoiu
Summary: PCOS is a complex disorder affecting 5% to 10% of women worldwide, with cardiovascular comorbidities such as endothelial dysfunction and atherosclerosis. Oxidative stress plays a key role in increasing CVD risk among PCOS patients, highlighting the potential benefits of antioxidant therapy.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Nutrition & Dietetics
Young-Ae Cho, Jeong-Hwa Choi
Summary: The study investigated the association between carbohydrate intake and metabolic syndrome in Korean women, finding that high carbohydrate intake is associated with an increased risk of metabolic syndrome, particularly abdominal obesity.
Review
Biochemistry & Molecular Biology
Mihaela-Andreea Podeanu, Adina Turcu-Stiolica, Mihaela Simona Subtirelu, Mioara Desdemona Stepan, Claudiu-Marinel Ionele, Dan-Ionut Gheonea, Bianca Stefanita Vintilescu, Raluca Elena Sandu
Summary: The study suggests that C-reactive protein (CRP) is a reliable marker for detecting inflammation in pediatric patients with metabolic syndrome (MetS). However, it may not be very accurate in distinguishing between patients with MetS and those who are obese.
Article
Psychology, Multidisciplinary
Peiwen Zhang, Wenke Zhao, Lan Shi, Yu Wang, Hong Sun, Zhen Sun
Summary: This study uses the MFI-16 scale to investigate the fatigue status of pilots and tests the reliability and validity of the scale. The findings show that most pilots experience mild fatigue or above. The study also improves the fatigue coefficient model and finds that different flights have positive effects on pilots' fatigue.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Immunology
Mark Slevin, Nima Heidari, Leonard Azamfirei
Summary: Monomeric C-reactive protein (mCRP) plays a critical role in the development of diseases caused by inflammation. Its tissue and cellular distribution are associated with inflammation and the progression of neurological and cardiovascular complications. Current research has also identified the diagnostic and prognostic potential of mCRP, making it a potential target for future therapeutic interventions.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Computer Science, Cybernetics
Kassandra Kim Yoke Soo, Timothy J. Mavin, Yoriko Kikkawa
Summary: The research compared different methods of pilot learning about aircraft automation systems, revealing gaps between training programs and trainees' actual experiences. Recommendations for possible modifications to current pilot training were discussed.
INTERNATIONAL JOURNAL OF HUMAN-COMPUTER INTERACTION
(2021)
Article
Nutrition & Dietetics
Huan Yu, Qiaorui Wen, Jun Lv, Dianjianyi Sun, Yuan Ma, Sailimai Man, Jianchun Yin, Mingkun Tong, Bo Wang, Canqing Yu, Liming Li
Summary: This study examines the impact of dietary patterns reflecting C-reactive protein (CRP) on metabolic syndrome (MetS) in the Chinese population. The results suggest that a CRP-related dietary pattern is positively associated with the risk of MetS, with higher scores indicating higher risk.
Article
Nutrition & Dietetics
Wojciech J. Bilinski, Anna Stefanska, Lukasz Szternel, Katarzyna Bergmann, Joanna Siodmiak, Magdalena Krintus, Przemyslaw T. Paradowski, Grazyna Sypniewska
Summary: The associations between individual components of metabolic syndrome (MetS) and bone health in children are complex, and data on this topic are sparse and inconsistent. In prepubertal girls, insulin resistance exerts a dominant negative impact on bone resorption, and inflammation factor CRP is weakly related to bone resorption in girls.
Article
Cardiac & Cardiovascular Systems
Erik S. G. Stroes, Harold E. Bays, Maciej Banach, Alberico L. Catapano, P. Barton Duell, Ulrich Laufs, G. B. John Mancini, Kausik K. Ray, William J. Sasiela, Yang Zhang, Antonio M. Gotto
Summary: This study demonstrates that bempedoic acid can reduce hsCRP levels in patients at risk of atherosclerotic cardiovascular disease. The changes in hsCRP and LDL-C are related, but the effect of bempedoic acid on hsCRP is independent of LDL-C lowering.
Review
Endocrinology & Metabolism
Bashir Ahmad Laway, Mohammad Salem Baba
Summary: Sheehan syndrome caused by postpartum hemorrhage leads to pituitary hormone deficiency, resulting in various abnormalities including lipid and glucose abnormalities, increased body fat, insulin resistance, coagulation abnormalities, increased leptin concentration, low-grade inflammation, and endothelial dysfunction. Replacement with growth hormone in addition to standard hormone replacement improves the cardiometabolic profile of patients with Sheehan syndrome.
FRONTIERS IN ENDOCRINOLOGY
(2023)