Article
Multidisciplinary Sciences
Vasily Marchenko, Alexey Danilenko, Natalia Kolosova, Maria Bragina, Marina Molchanova, Yuliya Bulanovich, Vladimir Gorodov, Sergey Leonov, Andrey Gudymo, Galina Onkhonova, Svetlana Svyatchenko, Alexander Ryzhikov
Summary: This study found coronaviruses in birds in Russia with a 12% detection rate, including both Gammacoronavirus and Deltacoronavirus. Further research on the spread and diversity of coronaviruses among birds is warranted.
SCIENTIFIC REPORTS
(2022)
Article
Agriculture, Dairy & Animal Science
Sheng Yuan, Qing Cheng, Jinyue Guo, Zhili Li, Jing Yang, Congying Wang, Zhipeng Liang, Xinyu Zhang, Hai Yu, Yong Li, Shujian Huang, Feng Wen
Summary: This study reports the genetic characteristics of two recent outbreaks of avian infectious bronchitis virus (IBV) in southern China, emphasizing the need for enhanced surveillance and the development of novel vaccines for IBV control.
Article
Microbiology
Eliana Icochea, Rosa Gonzalez, Gina Castro-Sanguinetti, Lenin Maturrano, Luis Alzamora, Luiz Sesti, Jorge Chacon, Juan More-Bayona
Summary: This study analyzed 200 samples collected from suspected infected animals in Peru between January and August in 2015, and found circulation of GI-16 and GI-1 lineages of infectious bronchitis virus (IBV). The GI-16 isolates showed unique nucleotide and amino acid changes compared to their closest relatives, suggesting potential relevance for vaccine evasion. These findings highlight the importance of genetic surveillance in improving vaccination strategies against infectious bronchitis.
Article
Biochemistry & Molecular Biology
Kui Gu, Zengxu Song, Peng Ma, Ziwei Liao, Ming Yang, Changyu Zhou, Chao Li, Yu Zhao, Hao Li, Xin Yang, Changwei Lei, Hongning Wang
Summary: A rapid, simple, sensitive, and specific competitive ELISA (cELISA) was developed in this study for the detection of Avian coronavirus-infectious bronchitis virus (AvCoV-IBV) antibodies. The developed cELISA showed high consistency with commercial ELISA, fast operation, and high sensitivity, making it potential for disease monitoring and control.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Mengjiao Huang, Xuewei Zheng, Yunjing Zhang, Ruohan Wang, Xiaona Wei
Summary: This study investigated the impact of virulent or avirulent IBV infection on the avian host by analyzing the protein expression in chicken kidneys. The results showed distinct expression profiles between different IBV strains, with the IFN-I signaling pathway emerging as a critical response to IBV infection.
Article
Virology
Weifeng Yuan, Ting Lv, Weiwei Jiang, Yuechi Hou, Qingyi Wang, Jinlian Ren, Lei Fan, Bin Xiang, Qiuyan Lin, Chan Ding, Tao Ren, Libin Chen
Summary: From January 2021 to June 2022, 15 strains of the infectious bronchitis virus (IBV) were isolated from chicken tissue samples collected in southern China. These strains mainly belonged to the QX type and showed recombination events in the S1 gene. The isolated strains caused respiratory symptoms in chickens and available vaccines were found ineffective against these prevalent strains, contributing to the continued spread of IBV.
Article
Virology
Alexandre Flageul, Chantal Allee, Celine Courtillon, Veronique Beven, Helene Quenault, Yannick Blanchard, Michel Amelot, David Courtois, Sjaak De Wit, Nicolas Eterradossi, Beatrice Grasland, Paul A. Brown
Summary: Despite the use of many live IBV vaccines, the Infectious Bronchitis virus (IBV) still causes significant economic losses in the chicken industry. Vaccine-induced partial protection may contribute to the emergence of new IBV strains. Through experiments on chickens, it was found that the IBV virus evolved rapidly in both vaccinated and non-vaccinated birds, but the genetic changes selected and their locations were different between the two groups.
Article
Biochemistry & Molecular Biology
Chenlu Feng, Cheng Huang, Yan Shi, Xiaona Gao, Zhihua Lu, Ruoyun Tang, Qiurong Qi, Yufan Shen, Guyue Li, Yun Shi, Ping Liu, Xiaoquan Guo
Summary: This study successfully prepared specific rabbit anti-chicken Beclin1 polyclonal antibodies and detected changes in tissues of diseased chickens infected with NIBV. This lays the foundation for further research on the role of Beclin1 in avian diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Veterinary Sciences
Kannan Ganapathy
Summary: Mucosal immunity is crucial for preventing infection and clearing the IBV virus, playing a key role in various immune responses, especially in the trachea. The interaction of mucins and cellular immunity enhances defense against IBV.
Article
Agriculture, Dairy & Animal Science
Wenjun Yan, Rongbin Qiu, Fuyan Wang, Xue Fu, Hao Li, Pengfei Cui, Yaru Zhai, Chun Li, Lan Zhang, Kui Gu, Lei Zuo, Changwei Lei, Hongning Wang, Xin Yang
Summary: Avian infectious bronchitis (IB), caused by avian infectious bronchitis virus (IBV), is a highly contagious disease that poses a serious threat to the poultry industry worldwide. A novel recombinant virus, CK/CH/SCMY/160315, derived from different live attenuated vaccine strains, has led to outbreaks in vaccinated chicken populations in China with various symptoms such as listlessness and sneezing. Pathogenicity analysis confirmed the high infectivity and harmfulness of this new strain.
Article
Virology
Na Xing, Zhisheng Wang, Jichun Wang, Mariana Nascimento, Anan Jongkaewwattana, Jakob Trimpert, Nikolaus Osterrieder, Dusan Kunec
Summary: Reverse genetics systems based on bacterial artificial chromosomes (BACs) are essential tools in coronavirus research. In this study, a reverse genetics system was established for the avian coronavirus strain Beaudette, which is extensively studied. The infectious clone of the Beaudette strain was constructed as a BAC, allowing the recovery of an infectious virus identical to the parental virus. The system was used to generate reporter viruses expressing enhanced green fluorescent protein (EGFP), which can serve as a valuable tool for studying virus replication and developing antiviral drugs.
JOURNAL OF VIROLOGY
(2022)
Article
Veterinary Sciences
Basim Manswr, Christopher Ball, Anne Forrester, Julian Chantrey, Kannan Ganapathy
Summary: This study showed differences in immune responses and viral loads to infectious bronchitis virus infection among different commercial broiler chicken lines, which may be influenced by levels of maternal antibodies, growth rates, and other inherent host genetic factors.
RESEARCH IN VETERINARY SCIENCE
(2021)
Review
Veterinary Sciences
Jose A. Quinteros, Jagoda Ignjatovic, Kapil K. Chousalkar, Amir H. Noormohammadi, Glenn F. Browning
Summary: Australian IBVs have evolved separately, leading to a range of unique strains with changes in tissue tropism, pathogenicity, antigenicity, and gene arrangement, including the emergence of novel genotypes GIII and GV. Various factors, such as vaccinations, genetic recombination, and gene mutations, have contributed to the complexity of the IBV population. This genetic diversity provides insight into vaccine development for controlling coronaviruses, including SARS-CoV-2.
Article
Virology
Liyang Zhao, Yusi Li, Wenjuan Yi, Kuo Yan, Chao Yang, Sridhar Radhakrishnan, Rui Li, Ruirong Tan, Gang Fan, Mengyuan Dai, Miao Liu, Ning-Yi Shao
Summary: This study investigated the impact of different classes of antihypertension drugs on mortality among hospitalized hypertensive patients infected with COVID-19. The results showed that ARB and CCB drugs significantly increased the survival rate, while ACE inhibitors/beta-blockers/diuretics had no effect on COVID-19-related mortality.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Microbiology
Hai-Chang Yin, Zhen-Dong Liu, Wei-Wei Zhang, Qing-Zhu Yang, Tian-Fei Yu, Xin-Jie Jiang
Summary: This study revealed the resistance mechanism of SPF chicken intestinal microbiota to nephropathogenic IBV infection, providing new ideas for preventing and controlling nephropathogenic IBV.
Article
Veterinary Sciences
A. M. Ghetas, G. E. Thaxton, C. Breedlove, V. L. van Santen, H. Toro
Article
Veterinary Sciences
H. Toro, V. L. van Santen, A. M. Ghetas, K. S. Joiner
Article
Veterinary Sciences
Eunice N. Ndegwa, Samantha N. Bartlett, Haroldo Toro, Kellye S. Joiner, Vicky L. van Santen
Article
Veterinary Sciences
H. Toro, V. L. van Santen, C. Breedlove
Article
Immunology
Fatma Eldemery, Kellye S. Joiner, Haroldo Toro, Vicky L. van Santen
Correction
Genetics & Heredity
Taejoong Kim, Henry D. Hunt, Mark S. Parcells, Vicky van Santen, Sandra J. Ewald
Article
Genetics & Heredity
Taejoong Kim, Henry D. Hunt, Mark S. Parcells, Vicky van Santen, Sandra J. Ewald
Article
Veterinary Sciences
R. A. Zegpi, S. L. Gulley, V. L. van Santen, K. S. Joiner, H. Toro
Article
Veterinary Sciences
F. Saiada, F. Eldemery, A. R. A. Zegpi, S. L. Gulley, A. Mishra, V. L. van Santen, H. Toro
Article
Veterinary Sciences
R. A. Zegpi, C. Breedlove, V. L. van Santen, C. R. Rasmussen-Ivey, H. Toro
Article
Veterinary Sciences
A. M. Ghetas, V. L. van Santen, K. Joiner, H. Toro
Article
Veterinary Sciences
R. A. Zegpi, L. He, Q. Yu, K. S. Joiner, V. L. van Santen, H. Toro
Article
Veterinary Sciences
R. A. Zegpi, K. S. Joiner, V. L. van Santen, H. Toro
Article
Veterinary Sciences
Farjana Saiada, Rodrigo A. Gallardo, H. L. Shivaprasad, Charles Corsiglia, Vicky L. van Santen
Article
Veterinary Sciences
Fatma Eldemery, Yufeng Li, Qingzhong Yu, Vicky L. van Santen, Haroldo Toro