期刊
AUSTRALIAN JOURNAL OF CHEMISTRY
卷 66, 期 2, 页码 199-207出版社
CSIRO PUBLISHING
DOI: 10.1071/CH12440
关键词
-
资金
- Grants-in-Aid for Scientific Research [21106001, 21106002] Funding Source: KAKEN
A continuous flow microreactor method for generating and carrying out reactions on pyridyllithiums has been developed based on Br/Li exchange reactions of bromopyridines and dibromopyridines. The reactions can be carried out without using cryogenic conditions by virtue of short residence times and efficient heat transfer, while very low temperatures such as -78 or -110 degrees C are required for conventional batch macro methods. Moreover, sequential introduction of two different electrophiles has been successfully achieved using dibromopyridines in an integrated flow microreactor system composed of four micromixers and four microtube reactors.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据