Non-clinical safety evaluation of repeated intramuscular administration of the AS15 immunostimulant combined with various antigens in rabbits and cynomolgus monkeys
出版年份 2015 全文链接
标题
Non-clinical safety evaluation of repeated intramuscular administration of the AS15 immunostimulant combined with various antigens in rabbits and cynomolgus monkeys
作者
关键词
-
出版物
JOURNAL OF APPLIED TOXICOLOGY
Volume 36, Issue 2, Pages 238-256
出版商
Wiley
发表日期
2015-06-02
DOI
10.1002/jat.3167
参考文献
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- (2015) Lawrence Segal et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
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- (2013) Caihua Xu et al. PLoS One
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- (2012) Erika Hamilton et al. Journal of Translational Medicine
- Testicular Development in Cynomolgus Monkeys
- (2012) Emiko Haruyama et al. TOXICOLOGIC PATHOLOGY
- Assessment of Circulating Hormones in Regulatory Toxicity Studies II. Male Reproductive Hormones
- (2012) Robert E. Chapin et al. TOXICOLOGIC PATHOLOGY
- Study designs for the nonclinical safety testing of new vaccine products
- (2012) Roy Forster JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
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- (2011) Marijo Bilusic et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
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- (2011) Sandra Morel et al. VACCINE
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- (2011) Genevieve M. Weir et al. Cancers
- Vaccines and Immunotherapeutics for the Treatment of Malignant Disease
- (2010) Joel F. Aldrich et al. Clinical & Developmental Immunology
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- (2008) Zhaoli Lane et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
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- (2008) Celine Thuilliez et al. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
- Phase 1 Trial of AMA1-C1/Alhydrogel plus CPG 7909: An Asexual Blood-Stage Vaccine for Plasmodium falciparum Malaria
- (2008) Gregory E. D. Mullen et al. PLoS One
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