Article
Cardiac & Cardiovascular Systems
Joost P. van Melle, Jolien W. Roos-Hesselink, Manish Bansal, Otto Kamp, Marwa Meshaal, Jiri Pudich, Vlatka Reskovic Luksic, Regino Rodriguez-Alvarez, Anita Sadeghpour, Jadranka Separovic Hanzevacki, Rouguiatou Sow, Ana Teresa Tim, Marisa Trabulo Morgado, Michele De Bonis, Cecile Laroche, Eric Boersma, Patrizio Lancellotti, Gilbert Habib
Summary: Congenital heart disease (CHD) patients with infective endocarditis (IE) have better survival rates compared to non-CHD patients. CHD patients are younger and have fewer comorbidities. Positive blood cultures for Streptococcus viridans and a higher prevalence of dental procedures were observed in CHD patients.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Immunology
Michelle Mahony, David Lean, Lily Pham, Robert Horvath, Jessica Suna, Cameron Ward, Sundar Veerappan, Kathryn Versluis, Clare Nourse
Summary: The incidence of infective endocarditis in children in Queensland is increasing, with congenital heart disease being the most common risk factor and Staphylococcus aureus the most common responsible organism. Aboriginal or Torres Strait Islander children are over-represented, but mortality remains low.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Stefanie Katharina Schuler, Pierre Alex Crisinel, Raphael Joye, Marie Rohr, Sabrina Bressieux-Degueldre, Martin Glockler, Paolo Paioni, Philipp K. A. Agyeman, Walter Knirsch
Summary: This study retrospectively analyzed the epidemiology and clinical outcomes of infective endocarditis in children aged <18 years in Switzerland from 2011 to 2020. The results showed that 58% of the 69 patients were diagnosed with definite infective endocarditis, and 42% were possible cases. The high morbidity and high rate of complications were associated with Staphylococcus aureus infections.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Hoorak Poorzand, Fatemeh Hamidi, Fereshte Sheybani, Fereshteh Ghaderi, Afsoon Fazlinezhad, Hedieh Alimi, Leila Bigdelu, Saeede Khosravi Bizhaem
Summary: The study aimed to determine the clinical characteristics and echocardiographic features of patients with IE. The short- and long-term prognosis for IE was poor, with heart failure and septic shock as predictors for in-hospital and 1-year mortality. Staphylococcus aureus was the most common causative pathogen.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Eva Havers-Borgersen, Jawad H. Butt, Morten Smerup, Gunnar H. Gislason, Christian Torp-Pedersen, Mathis Groning, Michael Rahbek Schmidt, Lars Sondergaard, Lars Kober, Emil L. Fosbol
Summary: Patients with tetralogy of Fallot (ToF) are at increased risk of infective endocarditis (IE), particularly those who undergo pulmonary valve replacement (PVR). Limited data exist on the long-term risk of IE, but the study confirms an association between PVR and increased incidence of IE.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Review
Cardiac & Cardiovascular Systems
Mansoor Khaledi, Fatemeh Sameni, Hamed Afkhami, Jaber Hemmati, Aram Asareh Zadegan Dezfuli, Mohammad-Javad Sanae, Majid Validi
Summary: Infective endocarditis is a severe disease associated with high mortality. HACEK organisms, gram-negative bacteria found in the mouth and upper respiratory tract, can cause a wide range of infections, including endocarditis. Preventive measures such as oral hygiene and prophylactic drug use should be taken to control and prevent HACEK-induced endocarditis.
JOURNAL OF CARDIOTHORACIC SURGERY
(2022)
Article
Public, Environmental & Occupational Health
Mazin Barry, Syed Abdul Bari, Muhammad Yasin Akhtar, Faizah Al Nahdi, Richilda Erlandez, Abdullah Al Khushail, Yahya Al Hebaishi
Summary: This study investigated the clinical and microbiological characteristics of infective endocarditis in a cardiac center in Saudi Arabia over a 5-year period, revealing common symptoms of fever and murmurs, and the most prevalent pathogens being Staphylococcus aureus and Streptococcus viridans. Surgical intervention was performed in 26% of cases, with an overall in-hospital mortality rate of 6.76%.
JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH
(2021)
Article
Immunology
Ulrika Snygg-Martin, Kok Wai Giang, Mikael Dellborg, Josefina Robertson, Zacharias Mandalenakis
Summary: Patients with congenital heart disease have a higher cumulative incidence of infective endocarditis compared to controls, and this incidence increases with age. The incidence of infective endocarditis varies by age but not by birth year.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Cardiac & Cardiovascular Systems
Eva Havers-Borgersen, Jawad H. Butt, Lauge ostergaard, Jeppe K. Petersen, Christian Torp-Pedersen, Lars Kober, Emil L. Fosbol
Summary: Patients with congenital heart disease (CHD) have a higher risk of infective endocarditis (IE) compared to the general population. This observational cohort study in Denmark found that the risk of IE varied among different types of CHD. Factors associated with IE in CHD patients included male sex, cyanosis, cardiac prostheses, chronic kidney disease, and cardiac implantable electronic devices. This highlights the importance of implementing preventive measures for CHD patients.
AMERICAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Clara Stammnitz, Doerte Huscher, Ulrike M. M. Bauer, Aleksandra Urban, Johannes Nordmeyer, Stephan Schubert, Joachim Photiadis, Felix Berger, Sabine Klaassen
Summary: This study aimed to identify specific long-term risk factors for infective endocarditis (IE) in patients with congenital heart disease after pulmonary valve replacements. The study found that bovine jugular vein valves had the highest risk of IE, while Edwards Sapien and mechanical valves were used less frequently and remained without IE.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Rodolfo Citro, Kwan-Leung Chan, Marcelo Haertel Miglioranza, Cecile Laroche, Rossella Maria Benvenga, Shumaila Furnaz, Julien Magne, Carmen Olmos, Bernard P. Paelinck, Agnes Pasquet, Cornelia Piper, Antonio Salsano, Arnaud Savoure, Seung Woo Park, Piotr Szymanski, Pierre Tattevin, Nuria Vallejo Camazon, Patrizio Lancellotti, Gilbert Habib
Summary: The aim of this study was to compare the clinical course and outcome of patients with recurrent versus first-episode infective endocarditis (IE). The results showed that there were similar in-hospital and 1-year mortality rates between patients with recurrent and first-episode IE, and they shared similar predictors of poor outcome.
Article
Cardiac & Cardiovascular Systems
Moustafa Rashed, Ghina Fakhri, Rana Zareef, Nour Abdul Halim, Mohamed Ahmed, Ghassan Dbaibo, Issam El-Rassi, Fadi Bitar, Mariam Toufic Arabi
Summary: In this study, a 20-year experience of a major referral tertiary care center in diagnosing and treating pediatric patients with infective endocarditis is presented. The medical records of 65 patients were comprehensively reviewed, and it was found that more than half of the patients had vegetation evident on echocardiography. The most commonly affected valve was the pulmonary valve.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Reuben K. Mutagaywa, Josephine C. Vroon, Lulu Fundikira, Anna Maria Wind, Peter Kunambi, Joel Manyahi, Apollinary Kamuhabwa, Gideon Kwesigabo, Steven A. J. Chamuleau, Maarten J. Cramer, Pilly Chillo
Summary: Despite advances in diagnostic and treatment, morbidity and mortality due to infective endocarditis (IE) has not decreased. There is a discrepancy in epidemiology of IE between developed and developing countries. Over the last years, increased early detection and consequently prevalence of rheumatic heart disease (RHD) and congenital heart disease (CHD) which are considered predisposing conditions for IE, is noted. This review shows a scarcity of studies on IE in developing countries. Rheumatic heart disease and congenital heart disease are common predisposing conditions. Other risk factors are prosthetic valves, degenerative valve disease (DVD), intravenous drug use, and human immunodeficiency virus infection. While the proportion of IE cases caused by Streptococcus and Staphylococcus has increased, the number of negative blood culture (NBC) and patients getting surgery has decreased. Mortality has not changed over time. Timely diagnosis and management of patients with RHD and CHD and comprehensive management of IE are warranted.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Immunology
Michael M. Dagher, Emily M. Eichenberger, Kateena L. Addae-Konadu, Sarah K. Dotters-Katz, Celia L. Kohler, Vance G. Fowler, Jerome J. Federspiel
Summary: Maternity-associated IE does not appear to confer additional risk for adverse outcomes over nonmaternity-associated infection. Patients who deliver with IE have worse maternal and fetal outcomes than those whose deliveries are not complicated by IE.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Cardiac & Cardiovascular Systems
Reaksmei Ly, Fabrice Compain, Bamba Gaye, Florence Pontnau, Melissa Bouchard, Jean-Luc Mainardi, Laurence Iserin, David Lebeaux, Magalie Ladouceur
Summary: This study investigated the outcomes and risk factors of infective endocarditis in adult patients with congenital heart disease, revealing a lower mortality rate in patients with congenital heart disease compared to those without, but particularly high mortality among patients with complex congenital heart disease.
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE
(2021)
Article
Cardiac & Cardiovascular Systems
Ganesh Kasinadhuni, Akash Batta, Atit A. Gawalkar, Sudhanshu Budakoty, Ankush Gupta, Rajesh Vijayvergiya
Summary: Quantitative flow ratio (QFR) has good diagnostic performance compared to fractional flow reserve (FFR) for physiological assessment of intermediate coronary lesions. Its performance is significantly better than anatomical percent diameter stenosis (%DS).
Article
Computer Science, Information Systems
Avtar Singh, Harpreet Kaur, Navjot Kaur
Summary: Software Defined Networking (SDN) is a paradigm shift in the network industry, providing network engineers with centralized control and management capabilities. However, SDN is vulnerable to attacks such as DDoS, which can disrupt network availability. This paper focuses on the detection and mitigation of DDoS in SDN, achieving a substantial growth in accuracy compared to previous works. The results show that a hybrid SVM-RF algorithm performs better than individual machine learning algorithms, and the effectiveness of mitigation depends on the accuracy of detection.
CLUSTER COMPUTING-THE JOURNAL OF NETWORKS SOFTWARE TOOLS AND APPLICATIONS
(2023)
Review
Microbiology
Nitin Sharma, Pratyush Shekhar, Vikas Kumar, Harpreet Kaur, Vijay Jayasena
Summary: This article introduces the types of microbial pigments, methods to enhance their production, and their applications in cosmetics and therapy. It also addresses the challenges faced during commercial production and proposes potential solutions.
JOURNAL OF BASIC MICROBIOLOGY
(2023)
Article
Immunology
Manash Jyoti Kalita, Simanta Kalita, Partha Pratim Das, Gautam Hazarika, Kalpajit Dutta, Ankur Jyoti Deka, Juchidananda Bhuyan, Md Ghaznavi Idris, Bikash Narayan Choudhury, Harpreet Kaur, Subhash Medhi
Summary: This study investigated the association between vitamin D receptor (VDR) gene polymorphism and hepatitis B virus (HBV) infection and disease progression. The results showed that a specific single nucleotide polymorphism (SNP) in the VDR gene was associated with HBV infection and disease progression. Furthermore, the mutant genotype was found to be associated with downregulation of VDR expression and host immunomodulation.
Article
Gastroenterology & Hepatology
Harpreet Kaur, Syed Azmal Ali, Sarah P. Short, Christopher S. Williams, Jeremy A. Goettel, M. Kay Washington, Richard M. Peek Jr, Sari A. Acra, Fang Yan
Summary: This study used structure-functional analysis to identify a functional peptide of p40 protein that regulates the epigenetic program in intestinal epithelial cells for preventing colitis. The findings suggest that this functional peptide could maintain intestinal homeostasis.
Article
Multidisciplinary Sciences
Amar Johri, Mohammad Wasiq, Harpreet Kaur, Mohammad Asif
Summary: This study analyzed the behavior of users investing in the stock market through online applications and found that users' awareness, benefits & choice of investment, reliability, safety, risk-related factors, financial literacy, technical aspect, and dependency significantly influence their adoption behavior.
Article
Radiology, Nuclear Medicine & Medical Imaging
Anupam Lal, Rajesh Vijayvergiya, Manphool Singhal
Summary: Uterine artery embolization (UAE) is a technique used to manage obstetrical and gynecological issues. The preferred approach is transfemoral, either unilateral or bilateral, but unilateral puncture is favored due to lower risk of complications. Reverse loop catheters, such as Roberts uterine catheter (RUC) or Gandras catheter, can be used to access the ipsilateral uterine artery. Another method is to maneuver catheters to create a Waltman's loop/Simmon's reverse loop. The recent unavailability of RUC in the Indian market has necessitated the use of bilateral TFA or previously used catheters and techniques for unilateral TFA. Here, we describe a technique using a simple gentle curve catheter (Picard) to create a reverse curve loop for unilateral TFA in UAE.
INDIAN JOURNAL OF RADIOLOGY AND IMAGING
(2023)
Review
Obstetrics & Gynecology
Mishu Mangla, Emine A. Rahiman, Harpreet Kaur, Poojitha Kanikaram
Summary: Gestational trophoblastic neoplasia (GTN) simultaneously occurring and metastasizing in both the mother and the baby is extremely rare, posing a diagnostic dilemma for treating clinicians. Through an analysis of relevant cases, it was found that diagnosis in the mother often follows diagnosis in the baby after clinical manifestations occur. Understanding the different clinical presentations and factors for early diagnosis are crucial for treatment.
JOURNAL OF THE TURKISH-GERMAN GYNECOLOGICAL ASSOCIATION
(2023)
Article
Health Care Sciences & Services
Apoorva Pandey, Sapan Borah, Bhavik Chaudhary, Shweta Rana, Harpreet Singh, Anita Nadkarni, Harpreet Kaur
FRONTIERS IN DIGITAL HEALTH
(2023)
Article
Cardiac & Cardiovascular Systems
Ankush Gupta, Abhinav Shrivastava, Sanya Chhikara, Mamas A. Mamas, Rajesh Vijayvergiya, Ajay Swamy, Nalin K. Mahesh, Navreet Singh, Nitin Bajaj, Balwinder Singh, Daulat Singh Meena, Chandraket Singh
Summary: The study aimed to predict side branch restenosis (SBR) after angioplasty for complex unprotected distal left main bifurcation (UdLMB) lesions using optical coherence tomography (OCT). It found that side branch distal reference diameter and side branch stent expansion were independent predictors of SBR.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)
Review
Chemistry, Physical
Pankaj Singla, Harpreet Kaur, Saweta Garg, Navalpreet Kaur, Francesco Canfarotta, Rakesh Kumar Mahajan, Marloes Peeters
Summary: The rapid spread of the novel coronavirus COVID-19 has posed challenges for its diagnosis and treatments. This article reviews two emerging detection methods: functionalized gold nanoparticles and molecularly imprinted polymers, which offer fast, highly specific identification of SARS-CoV-2. These methods are compared to traditional techniques, highlighting the need for fast, reliable, low-cost, and portable diagnostic platforms.
MOLECULAR SYSTEMS DESIGN & ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Harpreet Kaur, Amrik Singh, Anand K. Tyagi, Dharamvir Singh Ahlawat
Summary: In this study, cobalt zinc nanoferrites (CZF) nanoparticles were successfully synthesized using the auto-ignition method. The structural, magnetic, and dielectric properties of the CZF nanoparticles were investigated. The results showed that the CZF nanoparticles exhibited good magnetic and dielectric properties, making them promising for applications in microwave devices and high-frequency energy storage.
BULLETIN OF MATERIALS SCIENCE
(2023)
Review
Chemistry, Physical
Pankaj Singla, Harpreet Kaur, Saweta Garg, Navalpreet Kaur, Francesco Canfarotta, Rakesh Kumar Mahajan, Marloes Peeters
Summary: The rapid detection of COVID-19 is crucial in preventing community transmission. Besides traditional RT-PCR tests, emerging methods such as functionalized gold nanoparticles and molecularly imprinted polymers offer fast and reliable identification of the virus. Gold nanoparticles can accurately detect the virus, while molecularly imprinted polymers can imprint the virus on a nanoplatform for detection. The operating characteristics of these emerging diagnostic platforms were compared and evaluated.
MOLECULAR SYSTEMS DESIGN & ENGINEERING
(2023)
Meeting Abstract
Gastroenterology & Hepatology
Harpreet Kaur, Syed Azmal Ali, Sarah P. Short, Christopher S. Williams, Jeremy A. Goettel, Sari Acra, Fang Yan
Article
Urology & Nephrology
Pavneet Selhi, Harmandeep Singh Chahal, Heena Wadhwa, Simran Kaur, Kanwarpal Selhi, Harpreet Kaur, Anil Kumar Kashyap, Akashdeep Singh
Summary: This study demonstrates the utility of fine needle aspiration cytology (FNAC) in the etiological diagnosis of pulmonary infections in renal allograft recipients with respiratory failure. The diagnostic yield of FNAC in this cohort was 77.1%, with various microorganisms identified. FNAC is a useful tool for establishing the etiological diagnosis of pulmonary lesions in renal transplant patients with respiratory failure.
INDIAN JOURNAL OF NEPHROLOGY
(2023)
