Article
Medicine, General & Internal
Zhijie Jian, Guolin Yao, Huafeng Guo, Hui Liu, Bolin Li, Bolang Yu, Jian Yang, Lele Cheng
Summary: This study aimed to investigate the association of coronary plaque compositions with rapid lesion volume progression in patients with type 2 diabetes mellitus. The results showed that baseline calcified plaque volume is an independent protective factor for the rapid progression of coronary atherosclerosis in these patients. Therefore, calcified plaque volume should be considered in risk stratification for patients with type 2 diabetes mellitus.
ANNALS OF MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Changjing Feng, Rui Chen, Siting Dong, Wei Deng, Shushen Lin, Xiaomei Zhu, Wangyan Liu, Yi Xu, Xiaohu Li, Yinsu Zhu
Summary: By analyzing clinical data and CCTA images of 400 patients, it was found that FAI and NCPB were independent risk factors for coronary plaque progression. Combining conventional parameters with radiomics features derived from CCTA can better predict plaque progression.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Wei-Hua Yin, Hong-Yue Wang, Yang Sun, Xiang-Nan Li, Zhong-Fei Lu, Yun-Qiang An, Zhi-Hui Hou, Jie Zhang, Xin-Shuang Ren, U. Joseph Schoepf, Yan Zhang, Bin Lu
Summary: The study found that the diamond-attenuation-sign (DAS) could more accurately identify unstable atherosclerotic plaques compared to the napkin-ring sign (NRS), and DAS was more frequently seen on CCTA exams.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Wei-Hua Yin, Hong-Yue Wang, Yang Sun, Xiang-Nan Li, Zhong-Fei Lu, Yun-Qiang An, Zhi-Hui Hou, Jie Zhang, Xin-Shuang Ren, U. Joseph Schoepf, Yan Zhang, Bin Lu
Summary: The study evaluated the accuracy of the diamond-attenuation-sign in identifying unstable atherosclerotic plaques, finding that both MP-DAS and NCP-NRS had high specificity and positive predictive value, with MP-DAS outperforming NCP-NRS in identifying unstable coronary lesions.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Gianluca Pontone, Alexia Rossi, Andrea Baggiano, Daniele Andreini, Edoardo Conte, Laura Fusini, Chaterine Gebhard, Mark G. Rabbat, Andrea Guaricci, Marco Guglielmo, Giuseppe Muscogiuri, Saima Mushtaq, Mouaz H. Al-Mallah, Daniel S. Berman, Matthew J. Budoff, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Eun Ju Chun, Pedro de Araujo Goncalves, Ilan Gottlieb, Martin Hadamitzky, Yong Jin Kim, Byoung Kwon Lee, Sang-Eun Lee, Erica Maffei, Hugo Marques, Habib Samady, Sanghoon Shin, Ji Min Sung, Alexander van Rosendael, Renu Virmani, Jeroen J. Bax, Jonathon A. Leipsic, Fay Y. Lin, James K. Min, Jagat Narula, Leslee J. Shaw, Hyuk-Jae Chang
Summary: This study aimed to develop and validate a practical CCTA risk score to predict medium-term disease progression in patients at a low-to-intermediate probability of CAD.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Vincent L. Aengevaeren, Arend Mosterd, Esmee A. Bakker, Thijs L. Braber, Hendrik M. Nathoe, Sanjay Sharma, Paul D. Thompson, Birgitta K. Velthuis, Thijs M. H. Eijsvogels
Summary: According to the study, the intensity rather than the volume of exercise is associated with the progression of coronary atherosclerosis in middle-aged and older male athletes. Vigorous intensity exercise is associated with less coronary artery calcification (CAC) progression, while very vigorous intensity exercise is associated with greater CAC and calcified plaque progression.
Article
Cardiac & Cardiovascular Systems
Emma J. Hollenberg, Fay Lin, Michael J. Blaha, Matthew J. Budoff, Inge J. van den Hoogen, Umberto Gianni, Yao Lu, A. Maxim Bax, Alexander R. van Rosendael, Sara W. Tantawy, Daniele Andreini, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Edoardo Conte, Pedro de Araujo Goncalves, Martin Hadamitzky, Erica Maffei, Gianluca Pontone, Sanghoon Shin, Yong-Jin Kim, Byoung Kwon Lee, Eun Ju Chun, Ji Min Sung, Alessia Gimelli, Sang-Eun Lee, Jeroen J. Bax, Daniel S. Berman, Stephanie L. Sellers, Jonathon A. Leipsic, Ron Blankstein, Jagat Narula, Hyuk-Jae Chang, Leslee J. Shaw
Summary: It remains unclear whether a coronary artery calcium (CAC) score alone is sufficient to determine the risk of obstructive and nonobstructive atherosclerotic plaque in symptomatic patients. This study found that the characterization of atherosclerotic disease burden by CAC score is imperfect, but subgroups of CAC scores showed pathogenic patterns of disease progression and stratified long-term prognostic risk.
JACC-CARDIOVASCULAR IMAGING
(2022)
Review
Cardiac & Cardiovascular Systems
Patrick W. Serruys, Hironori Hara, Scot Garg, Hideyuki Kawashima, Bjarne L. Norgaard, Marc R. Dweck, Jeroen J. Bax, Juhani Knuuti, Koen Nieman, Jonathon A. Leipsic, Saima Mushtaq, Daniele Andreini, Yoshinobu Onuma
Summary: Coronary computed tomography angiography (CTA) has undergone significant technological advancements and is now considered a high-accuracy substitute for conventional invasive coronary angiography in diagnosing and making treatment decisions for patients with suspected coronary artery disease.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Nutrition & Dietetics
Tsung-Ying Tsai, Pai-Feng Hsu, Cheng-Hsueh Wu, Shao-Sung Huang, Wan-Leong Chan, Shing-Jong Lin, Jaw-Wen Chen, Tse-Min Lu, Hsin-Bang Leu
Summary: Liver fibrosis scores, including NFS, FIB-4, and Forns score, are associated with the presence of coronary artery disease (CAD) plaques in subjects in early CAD stages. For disease progression, male gender, DBP, and NFS appear to be independently associated with coronary atherosclerosis plaque progression in subjects with low calcium scores.
Article
Radiology, Nuclear Medicine & Medical Imaging
David C. Rotzinger, Virginie Magnin, Allard C. van der Wal, Silke Grabherr, Salah D. Qanadli, Katarzyna Michaud
Summary: Multiphase postmortem CT angiography (PMCTA) can be used to detect plaque enhancement as a surrogate marker of inflammation, providing a noninvasive method for evaluating inflammation in coronary plaques.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Yannick Kaiser, Marwa Daghem, Evangelos Tzolos, Mohammed N. Meah, Mhairi K. Doris, Alistair J. Moss, Jacek Kwiecinski, Jeffrey Kroon, Nick S. Nurmohamed, Pim van der Harst, Philip D. Adamson, Michelle C. Williams, Damini Dey, David E. Newby, Erik S. G. Stroes, Kang H. Zheng, Marc R. Dweck
Summary: Among patients with advanced stable coronary artery disease, elevated Lp(a) levels are associated with accelerated progression of coronary low-attenuation plaque (necrotic core). This finding may explain the increased risk of myocardial infarction in individuals with high Lp(a) levels and supports Lp(a) as a potential treatment target for atherosclerosis.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
F. Y. van Driest, C. M. Bijns, R. J. van der Geest, A. Broersen, J. Dijkstra, A. J. H. A. Scholte, J. W. Jukema
Summary: This study presents an overview of the use of serial coronary computed tomography angiography (CCTA) for predicting plaque progression and/or major adverse cardiac events (MACE). The findings suggest that quantitative baseline plaque features and quantitative plaque changes are more predictive than qualitative plaque features. However, further research is needed to understand the clinical implications and challenges of using serial CCTA.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Runlei Ma, Marly van Assen, Daan Ties, Gert Jan Pelgrim, Randy van Dijk, Grigory Sidorenkov, Peter M. A. van Ooijen, Pim van der Harst, Rozemarijn Vliegenthart
Summary: This study found that lesion-specific PCAT(MA) in arteries with plaque was higher than proximal PCAT(MA) in arteries without plaque, and lesion-specific PCAT(MA) was higher in non-calcified and mixed plaques compared to calcified plaques, and in minimal stenosis compared to severe.
EUROPEAN RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
A. Maxim Bax, Fay Y. Lin, Alexander R. van Rosendael, Xiaoyue Ma, Yao Lu, Inge J. van den Hoogen, Umberto Gianni, Sara W. Tantawy, Daniele Andreini, Matthew J. Budoff, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Edoardo Conte, Pedro de Araujo Goncalves, Ilan Gottlieb, Martin Hadamitzky, Jonathon A. Leipsic, Erica Maffei, Gianluca Pontone, Gregg Stone, Sanghoon Shin, Yong-Jin Kim, Byoung Kwon Lee, Eun Ju Chun, Ji Min Sung, Sang-Eun Lee, Daniel S. Berman, Jagat Narula, Hyuk-Jae Chang, Leslee J. Shaw
Summary: There are variations in the progression of atherosclerotic plaque between the left circumflex (LCx), right coronary artery (RCA), and left anterior descending (LAD). The LCx has less plaque progression compared to the RCA and LAD, and the LAD is associated with a higher risk of progression to obstructive coronary artery disease.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Hankun Yan, Na Zhao, Wenlei Geng, Zhihui Hou, Yang Gao, Bin Lu
Summary: There is an association between pericoronary fat attenuation index (FAI), plaque characteristics, and lesion-specific ischemia. The combination of FAI and plaque assessment improves the discrimination of ischemia compared with stenosis assessment alone.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)