Article
Pharmacology & Pharmacy
Min-Fei Sun, Jia-Ning Liao, Zhen-Yi Jing, Han Gao, Bin -Bin Shen, You-Fu Xu, Wei-Jie Fang
Summary: This study evaluated the degradation of the excipient glycerol during repeated use and improper storage and discovered a previously unknown impurity. Another excipient, mannitol, was found to be more stable than glycerol. The effects of degraded glycerol and mannitol on the stability of the biopharmaceutical thymopentin were also examined.
JOURNAL OF PHARMACEUTICAL ANALYSIS
(2022)
Article
Engineering, Environmental
Sanjeeb Mohapatra, Neha Sharma, Gayatree Mohapatra, Lokesh P. Padhye, Suparna Mukherji
Summary: In this study, wastewater samples from five WWTPs in western India were analyzed using fluorescence spectroscopy. The hydrophilic acid and hydrophilic neutral fractions were found to be more abundant than the hydrophilic base fraction in both influent and effluent wastewater streams. Trphtophan-like and tyrosine-like substances were also detected in the wastewater. LC-MS/MS analysis identified hundreds of DOM proteins in the influent and effluent streams, some of which were related to Alzheimer's and Huntington disease, serving as potential biomarkers for wastewater-based epidemiology.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Analytical
Sonia Medina, David Aunon, Jordan Lehoux, Thierry Durand, Celine Crauste, Angel Gil-Izquierdo
Summary: The study reveals that levels of HT-FAs in EVOO increase over time under both commercial room temperature and high temperature storage conditions, with the type and degree of unsaturation of fatty acids playing a role. In blends with refined oils, free HT levels decrease while esterified HT significantly increases.
MICROCHEMICAL JOURNAL
(2022)
Article
Fisheries
Cheng Zhou, Zhi-qiang Zhang, Lei Zhang, Ying Liu, Peng-fei Liu
Summary: The European sea bass showed the best growth and feeding performance at a temperature of 20 degrees C, indicating that temperature plays a significant role in promoting the growth and metabolism of this aquaculture species. Metabolomic analysis revealed important differential metabolites and metabolic pathways related to different temperature conditions, providing insights for improving production in industrial recirculating aquaculture systems.
Article
Chemistry, Applied
A. Rego, I. Coelho, C. Motta, C. Cardoso, A. Gomes-Bispo, C. Afonso, N. M. Bandarra, J. A. L. Silva, I. Castanheira, J. A. M. Prates
Summary: Chub mackerel is an underutilised fish species that contains high levels of selenium and vitamin B12, which are beneficial for preventing cognitive decline and dementia. The content of these nutrients varies seasonally, emphasizing the importance of a year-round assessment to provide accurate dietary recommendations.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Biochemistry & Molecular Biology
Yangfan Leng, Liubin Yang, Hangxin Zhu, Dongqin Li, Siyi Pan, Fang Yuan
Summary: In this study, blueberry extracellular vesicles (B-EVs) were collected and purified, and their stability during food storage and processing conditions was evaluated. The results showed that B-EVs had desirable properties and could affect human intestinal function.
Article
Biochemical Research Methods
Dorota Garwolinska, Michal Mlynarczyk, Agata Kot-Wasik, Weronika Hewelt-Belka
Summary: The study found that storage of human milk samples at 4 degrees Celsius for 4 days and subjecting them to three freeze-thaw cycles can lead to changes in lipid content. Differences in levels of certain lipid species between samples stored at -20 degrees Celsius and -80 degrees Celsius were not statistically significant, and individual variance remained consistent regardless of sample storage conditions. Storing HM samples at -20 degrees Celsius for up to 3 weeks and at -80 degrees Celsius for up to 12 weeks ensures sample lipidome stability.
JOURNAL OF PROTEOME RESEARCH
(2022)
Article
Environmental Sciences
Klaudia Godlewska, Piotr Stepnowski, Monika Paszkiewicz
Summary: Passive sampling is a cost-effective strategy for quantifying micropollutants in water environments. In this study, carbon nanotubes were used as sorbents in POCIS-like samplers, and their effectiveness in field sampling was proven. The use of CNTs-PSDs allowed for the determination of various chemicals in surface waters.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Analytical
Xuefei Zhong, Shruti Nayak, Lili Guo, Shivkumar Raidas, Yunlong Zhao, Rachel Weiss, Matthew Andisik, Chinnasamy Elango, Giane Sumner, Susan C. Irvin, Michael A. Partridge, Hong Yan, Sook E. Yen, Haibo Qiu, Yuan Mao, Albert Torri, Ning Li
Summary: REGEN-COV, a cocktail of two human monoclonal antibodies, has shown promising results in reducing SARS-CoV-2 viral load in COVID-19 patients. A liquid chromatography-mass spectrometry method was developed for the determination of REGEN-COV concentrations in serum samples from patients participating in clinical trials. The concentrations measured by this method were comparable to those measured by a validated immunoassay.
ANALYTICAL CHEMISTRY
(2021)
Article
Biochemical Research Methods
Dune Olivier, Frank van Der Kooy, Minja Gerber
Summary: This study aimed to develop a sensitive quality control method for Artemisia afra infusions by validating a liquid chromatography electrospray ionisation tandem mass spectrometry (LC-ESI-MS/MS) method and quantitatively comparing six marker compounds in A. afra samples collected from different locations and over a 12-month period.
PHYTOCHEMICAL ANALYSIS
(2023)
Article
Chemistry, Applied
Bolin Mou, Wenqing Yang, Shuang Song, Cai Shen, Worawan Panpipat, Oi-Ming Lai, Chin-Ping Tan, Ling-Zhi Cheong
Summary: Milk processing technologies decrease the content of phospholipids in milk, with boiling and freezing showing the highest reduction.
Article
Plant Sciences
Aliu Moomin, Wendy R. Russell, Rachel M. Knott, Lorraine Scobbie, Kwesi Boadu Mensah, Paa Kofi Tawiah Adu-Gyamfi, Susan J. Duthie
Summary: This study investigated the effects of extraction method, season, and storage conditions on the phytochemical composition of Terminalia ivorensis, providing important information on its potential benefits.
Article
Food Science & Technology
Nouara Abdelli, Enas Mekawi, Mohammed Ebrahim Abdel-Alim, Nesreen Saad Salim, Mahran El-Nagar, Sati Y. Al-Dalain, Ridab Adlan Abdalla, Ganesan Nagarajan, Emad Fadhal, Rashid I. H. Ibrahim, Eman Afkar, Mohamed K. Morsy
Summary: The study assessed and utilized garlic nanoparticles as a natural antioxidant to enhance the stability and extend the shelf life of sunflower oil under high temperature conditions. The results demonstrated that garlic nanoparticles exhibited excellent antioxidant properties.
Article
Multidisciplinary Sciences
Maciej A. Zwieniecki, Anna M. Davidson, Jessica Orozco, Katelyn B. Cooper, Paula Guzman-Delgado
Summary: Successful yield in orchards is closely related to the level of non-structural carbohydrates (NSC). High levels of NSC are associated with high yield, while low levels are associated with low yield. Monthly NSC levels play an important role in predicting yield and should be monitored for orchard management.
SCIENTIFIC REPORTS
(2022)
Article
Food Science & Technology
Yuksel Bayram, Kubra Ozkan, Osman Sagdic
Summary: In this study, unripe grapes were used to produce verjuice powder, which was encapsulated with maltodextrin and pectin. The powders were evaluated for their properties and retention of phenolic compounds. The results showed that pectin encapsulation had higher phenolic retention compared to maltodextrin encapsulation. This study suggests that waste from viticulture can be transformed into valuable powders for potential applications and contribute to sustainable agriculture.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Ulrike Jost, Bjoern Andreessen, Dirk Michalik, Alexander Steinbuechel, Udo Kragl
ENGINEERING IN LIFE SCIENCES
(2017)
Article
Chemistry, Organic
Anna Reimer, Severin Wedde, Svenja Staudt, Sandy Schmidt, Diana Hoeffer, Werner Hummel, Udo Kragl, Uwe T. Bornscheuer, Harald Groeger
JOURNAL OF HETEROCYCLIC CHEMISTRY
(2017)
Article
Biotechnology & Applied Microbiology
Claudia Engelmann, Udo Kragl
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2018)
Article
Chemistry, Physical
Sina Kummer, Sandra Klembt, Wolfgang Ruth, Udo Kragl
JOURNAL OF MOLECULAR LIQUIDS
(2017)
Article
Biochemical Research Methods
Lars-Erik Meyer, Anja Gummesson, Udo Kragl, Jan von Langermann
BIOTECHNOLOGY JOURNAL
(2019)
Article
Chemistry, Multidisciplinary
Mai N. Nguyen, Udo Kragl, Dirk Michalik, Ralf Ludwig, Dirk Hollmann
Article
Multidisciplinary Sciences
Johanna Claus, Andreas Brietzke, Celina Lehnert, Stefan Oschatz, Niels Grabow, Udo Kragl
Article
Food Science & Technology
Manuel Gronbach, Laura Krausser, Timo Broese, Christina Oppermann, Udo Kragl
Summary: The benefits of sublimation for natural product and food chemistry were described in this article. Sublimation can help to identify new plant constituents and fight food fraud by studying dried plant powders and extracts.
FOOD ANALYTICAL METHODS
(2021)
Article
Polymer Science
Ann Jastram, Tobias Lindner, Christian Luebbert, Gabriele Sadowski, Udo Kragl
Summary: This study focused on hydrogels synthesized by radical polymerization of imidazolium-based ionic liquids. The swelling and diffusion behavior of these hydrogels were investigated, showing strong swelling in water and ethanol with transport mechanisms deviating from Fickian-type behavior.
Article
Polymer Science
Johanna Romischke, Anton Scherkus, Michael Saemann, Simone Krueger, Rainer Bader, Udo Kragl, Johanna Meyer
Summary: Hydrogels have gained increasing interest in various fields, including their applications as immobilization matrices in (bio)catalysis and in the medical sector for drug delivery systems, contact lenses, biosensors, electrodes, and tissue engineering. Natural hydrogels from collagen, hyaluronic acid, and gelatin are known for their biocompatibility but often lack stability, reproducibility, and mechanical strength. Synthetic hydrogels, on the other hand, offer tunable swelling and mechanical properties, reproducibility, and lower costs.
Article
Polymer Science
Johanna Claus, Ann Jastram, Ewelina Piktel, Robert Bucki, Paul A. Janmey, Udo Kragl
Summary: The study found that out of the 11 monomers tested, 6 showed strong bactericidal activity against P. aeruginosa Xen 5. However, anionic, neutral, and zwitterionic representatives lost their function after polymerization, while cationic gels retained nearly 100% antibacterial activity. Crosslinking them into three-dimensional networks significantly increased the weak antibacterial activities.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Fridolin O. Sommer, Jana-Sophie Appelt, Ingo Barke, Sylvia Speller, Udo Kragl
Article
Chemistry, Multidisciplinary
Melanie Reiss, Andreas Brietzke, Thomas Eickner, Florian Stein, Alexander Vitlinger, Christian Vogel, Udo Kragl, Stefan Jopp
Article
Chemistry, Multidisciplinary
Julia Grosseheilmann, Udo Kragl
Review
Chemistry, Multidisciplinary
Annika Kottmann, Esteban Mejia, Therese Hemery, Johann Klein, Udo Kragl
CHEMISTRY-AN ASIAN JOURNAL
(2017)