Assessment of Compound Hepatotoxicity Using Human Plateable Cryopreserved Hepatocytes in a 1536-Well-Plate Format

The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform

(2010) Sunita J. Shukla et al.   DRUG DISCOVERY TODAY

Evaluation of Luciferin-Isopropyl Acetal as a CYP3A4 Substrate for Human Hepatocytes: Effects of Organic Solvents, Cytochrome P450 (P450) Inhibitors, and P450 Inducers

(2009) A. P. Li   DRUG METABOLISM AND DISPOSITION

An In Vitro Assay to Assess Transporter-Based Cholestatic Hepatotoxicity Using Sandwich-Cultured Rat Hepatocytes

(2009) J. H. Ansede et al.   DRUG METABOLISM AND DISPOSITION

In Vitro and in Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of America Perspective

(2009) V. Chu et al.   DRUG METABOLISM AND DISPOSITION

A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo

(2009) Anne S. Kienhuis et al.   TOXICOLOGY IN VITRO

Potassium Dichromate Induced Cytotoxicity, Genotoxicity and Oxidative Stress in Human Liver Carcinoma (HepG2) Cells

(2009) Anita Patlolla et al.   International Journal of Environmental Research and Public Health

Characterization of Diversity in Toxicity Mechanism Using in Vitro Cytotoxicity Assays in Quantitative High Throughput Screening

(2008) Ruili Huang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The role of earlyin vivotoxicity testing in drug discovery toxicology

(2008) Mark R Fielden et al.   Expert Opinion On Drug Safety

Investigations into the liver effects of ximelagatran using high content screening of primary human hepatocyte cultures

(2008) Edward K Ainscow et al.   Expert Opinion On Drug Safety

Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

(2008) Robert J. Kavlock et al.   RISK ANALYSIS

Transforming Environmental Health Protection

(2008) Francis S. Collins et al.   SCIENCE

Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

(2008) Jinghai J. Xu et al.   TOXICOLOGICAL SCIENCES

A bioluminescent cytotoxicity assay for assessment of membrane integrity using a proteolytic biomarker

(2008) Ming-Hsuang Cho et al.   TOXICOLOGY IN VITRO