The Inwardly Rectifying Potassium Channel Kir1.1: Development of Functional Assays to Identify and Characterize Channel Inhibitors

Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics

(2012) Haifeng Tang et al.   ACS Medicinal Chemistry Letters

Small-molecule modulators of inward rectifier K+ channels: recent advances and future possibilities

(2010) Gautam Bhave et al.   Future Medicinal Chemistry

Protein Binding-dependent Decreases in hERG Channel Blocker Potency Assessed by Whole-Cell Voltage Clamp in Serum

(2010) Michael Margulis et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

High-Throughput Screening Reveals a Small-Molecule Inhibitor of the Renal Outer Medullary Potassium Channel and Kir7.1

(2009) L. M. Lewis et al.   MOLECULAR PHARMACOLOGY

Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 A Resolution

(2009) X. Tao et al.   SCIENCE

Miniaturization and HTS of a FRET-Based Membrane Potential Assay for Kir Channel Inhibitors

(2008) Kelli Solly et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Madin-Darby Canine Kidney II Cells: A Pharmacologically Validated System for NPC1L1-Mediated Cholesterol Uptake

(2008) A. B. Weinglass et al.   MOLECULAR PHARMACOLOGY

Rare independent mutations in renal salt handling genes contribute to blood pressure variation

(2008) Weizhen Ji et al.   NATURE GENETICS

High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology

(2008) John Dunlop et al.   NATURE REVIEWS DRUG DISCOVERY