A New Model of Cuprizone-Mediated Demyelination/Remyelination

mTOR Signaling Inhibition Modulates Macrophage/Microglia-Mediated Neuroinflammation and Secondary Injury via Regulatory T Cells after Focal Ischemia

(2014) L. Xie et al.   JOURNAL OF IMMUNOLOGY

Conditional Ablation of Raptor or Rictor Has Differential Impact on Oligodendrocyte Differentiation and CNS Myelination

(2014) K. K. Bercury et al.   JOURNAL OF NEUROSCIENCE

Short-Term Cuprizone Feeding Induces Selective Amino Acid Deprivation with Concomitant Activation of an Integrated Stress Response in Oligodendrocytes

(2013) Johannes Goldberg et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Inactivation of mTORC1 in the Developing Brain Causes Microcephaly and Affects Gliogenesis

(2013) D. Cloetta et al.   JOURNAL OF NEUROSCIENCE

Sustained Activation of ERK1/2 MAPK in Oligodendrocytes and Schwann Cells Enhances Myelin Growth and Stimulates Oligodendrocyte Progenitor Expansion

(2013) A. Ishii et al.   JOURNAL OF NEUROSCIENCE

Signaling through ERK1/2 Controls Myelin Thickness during Myelin Repair in the Adult Central Nervous System

(2013) S. L. Fyffe-Maricich et al.   JOURNAL OF NEUROSCIENCE

Astrogliosis During Acute and Chronic Cuprizone Demyelination and Implications for Remyelination

(2012) Norah Hibbits et al.   ASN Neuro

Rapamycin encapsulated in dual-responsive micelles for cancer therapy

(2012) Yi-Chun Chen et al.   BIOMATERIALS

Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

(2012) Thomas Skripuletz et al.   BRAIN

Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation

(2012) Erwin A. van Vliet et al.   EPILEPSIA

S-Nitrosoglutathione Induces Ciliary Neurotrophic Factor Expression in Astrocytes, Which Has Implications to Protect the Central Nervous System under Pathological Conditions

(2012) Manjeet K. Paintlia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exogenous Leukemia Inhibitory Factor Stimulates Oligodendrocyte Progenitor Cell Proliferation and Enhances Hippocampal Remyelination

(2012) B. E. Deverman et al.   JOURNAL OF NEUROSCIENCE

Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts

(2011) Junjie Zou et al.   Journal of Cardiothoracic Surgery

Enhanced Delivery of Rapamycin by V156K-apoA-I High-Density Lipoprotein Inhibits Cellular Proatherogenic Effects and Senescence and Promotes Tissue Regeneration

(2011) K.-H. Cho   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A 3-in-1 Polymeric Micelle Nanocontainer for Poorly Water-Soluble Drugs

(2011) Ho-Chul Shin et al.   MOLECULAR PHARMACEUTICS

Characterisation of microglia during de- and remyelination: Can they create a repair promoting environment?

(2011) Elke Verena Voß et al.   NEUROBIOLOGY OF DISEASE

Dietary Vitamin D3 Supplements Reduce Demyelination in the Cuprizone Model

(2011) Stig Wergeland et al.   PLoS One

Inhibition of 5-lipoxygenase activity in mice during cuprizone-induced demyelination attenuates neuroinflammation, motor dysfunction and axonal damage

(2011) K. Yoshikawa et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Rostrocaudal Analysis of Corpus Callosum Demyelination and Axon Damage Across Disease Stages Refines Diffusion Tensor Imaging Correlations With Pathological Features

(2010) Mingqiang Xie et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

GAS6 Enhances Repair Following Cuprizone-Induced Demyelination

(2010) Vladislav Tsiperson et al.   PLoS One

The cuprizone animal model: new insights into an old story

(2009) Markus Kipp et al.   ACTA NEUROPATHOLOGICA

Activation of the Mammalian Target of Rapamycin (mTOR) Is Essential for Oligodendrocyte Differentiation

(2009) W. A. Tyler et al.   JOURNAL OF NEUROSCIENCE

Akt Signals through the Mammalian Target of Rapamycin Pathway to Regulate CNS Myelination

(2009) S. P. Narayanan et al.   JOURNAL OF NEUROSCIENCE

Chronic toxic demyelination in the central nervous system leads to axonal damage despite remyelination

(2009) Maren Lindner et al.   NEUROSCIENCE LETTERS

Amino acid regulation of TOR complex 1

(2008) Joseph Avruch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex

(2008) Ling-Hui Zeng et al.   ANNALS OF NEUROLOGY

Effects of dietary intervention on MRI activity, de- and remyelination in the cuprizone model for demyelination

(2008) Øivind Torkildsen et al.   EXPERIMENTAL NEUROLOGY

Constitutively Active Akt Induces Enhanced Myelination in the CNS

(2008) A. I. Flores et al.   JOURNAL OF NEUROSCIENCE