Article
Food Science & Technology
Tianci Jiang, Pengfei Li, Junwei Zhao, Lingling Dai, Di Sun, Meng Liu, Lin An, Liuqun Jia, Xiaogang Jing, Huan Wang, Shujun Wu, Yu Wang, Zhe Cheng
Summary: The study found that LCPUFAs can modulate the gut microbial composition of asthmatic mice, improve airway pathological features, and reduce interleukin 5 levels and airway PAS scores.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Food Science & Technology
Ruoya Zhou, Lina Zhang, Kai Zhang, Peng Zhou
Summary: This study investigated the difference in allergenicity between chicken egg and duck egg ovalbumin. It was found that chicken ovalbumin induced a stronger allergic reaction compared to duck ovalbumin, while duck ovalbumin showed a milder immune response and maintained the integrity of the intestinal barrier. Furthermore, cross-reactions were observed with consumption of duck ovalbumin in chicken ovalbumin allergic mice, but the allergic symptoms were milder.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Shimin Gu, Qiang Xie, Chen Chen, Chenglong Liu, Wentong Xue
Summary: This study used 16S rRNA sequencing to analyze the gut microbiota composition of peanut-allergic mice and found several bacterial groups that were significantly associated with peanut allergy, potentially serving as gut microbial signatures for peanut allergy.
Article
Food Science & Technology
Kan Gao, Lie Chen, Cailing Chen, Zuoguo Chen, Qiwen Zhang, Qiuling Fan, Yanjun Li, Su Chen
Summary: Food allergy is a significant public health and food safety issue caused by an amplified immune reaction to food antigens. Probiotics, such as Lactobacillus and Bifidobacterium, have been suggested as a potential strategy for alleviating allergic diseases. This study found that Leuconostoc mesenteroides strain WHH1141 improved food allergy symptoms and normalized immune responses in a mouse model. WHH1141 also restored gut microbiome composition and short-chain fatty acid levels, suggesting its potential as a therapeutic intervention for food allergy.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Ye-Ji Lee, Dong-Soon Im
Summary: This study compared the effects of LPA(2) antagonist and agonist in an experimental model of allergic asthma, finding that the drugs had different impacts on asthma-related indicators at different administration time points, demonstrating the multiple roles of LPA(2) in asthmatic responses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Multidisciplinary
Jiayuan Xu, Yongli Ye, Jian Ji, Jiadi Sun, Jia-Sheng Wang, Xiulan Sun
Summary: Gut microbiota affects the occurrence of food allergies by producing metabolites and modulating the immune system. This study found that specific metabolites and bacterial groups may be associated with the regulation of allergic responses in an ovalbumin-sensitive mouse model through metabolomic and microbiomic analyses.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Nutrition & Dietetics
Katleen Pinchaud, Zeeshan Hafeez, Sandrine Auger, Jean-Marc Chatel, Sead Chadi, Philippe Langella, Justine Paoli, Annie Dary-Mourot, Katy Maguin-Gate, Jean Luc Olivier
Summary: The study found that dietary arachidonic acid can alter gut microbiota, induce low-grade colic inflammation, and cause astrogliosis in the brain.
Article
Immunology
Wenhui Fu, Chen Chen, Qiang Xie, Shimin Gu, Sha Tao, Wentong Xue
Summary: This study investigated the effects of Pediococcus acidilactici XZ31 on wheat-induced allergy. The results showed that P. acidilactici XZ31 attenuated allergic responses, regulated immune balance, and reduced gluten-specific IgE production. It also modulated gut microbiota and increased the abundance of beneficial bacteria. This research provides a new strategy for treating wheat allergy.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Biology
Feliznando Isidro Cardenas-Torres, Francisco Cabrera-Chavez, Aldo Alejandro Arvizu-Flores, Lilian Karem Flores-Mendoza, Veronica Lopez-Teros, Humberto Astiazaran-Garcia, Martina Hilda Gracia-Valenzuela, Oscar Gerardo Figueroa-Salcido, Jesus Gilberto Aramburo-Galvez, Noe Ontiveros
Summary: The mouse model is valuable for studying IgE responses to food proteins. Intraperitoneal administration of protein triggers more robust and consistent IgE responses compared to intragastric administration. This study provides scientific evidence for the development of a reproducible mouse model for evaluating food allergies.
Article
Medicine, Research & Experimental
Mohammad Reza Madanipour, Mortaza Fatehi-Zardalou, Nastaran Rahimi, Sara Hemmati, Mojgan Alaeddini, Shahroo Etemad-Moghadam, Maryam Shayan, Sasan Dabiri, Ahmad Reza Dehpour
Summary: This study found that dapsone has anti-inflammatory effects on allergic rhinitis in mice, significantly reducing nasal symptoms caused by inflammation and showing improvement in histopathological analysis.
Article
Biochemistry & Molecular Biology
Weiyun Zheng, Mengmeng Duan, Jinhui Jia, Shuang Song, Chunqing Ai
Summary: The study demonstrated that low-molecular alginate from Laminaria japonica has a significant impact on reducing obesity and metabolic syndrome in high-fat diet-fed mice, by improving gut microbiota structure.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Nutrition & Dietetics
Kouya Hattori, Masahiro Akiyama, Natsumi Seki, Kyosuke Yakabe, Koji Hase, Yun-Gi Kim
Summary: Specific gut bacteria, such as Escherichia coli from the Enterobacteriaceae family, play a key role in suppressing sorbitol-induced diarrhea by degrading sorbitol in the intestine. The findings suggest that the gut microbiota's ability to respond to and break down sugar alcohols has implications for microbiome science, processed food science, and public health.
Article
Food Science & Technology
Lijun Yao, Peng Yang, Yue Lin, Decheng Bi, Boming Yu, Zhijian Lin, Yan Wu, Hong Xu, Zhangli Hu, Xu Xu
Summary: Alginate can alter the secondary structure of ovalbumin, alleviate allergic diarrhea and intestinal morphological damage, and restore the richness and diversity of gut microbiota, suggesting its potential as a protective agent for the intestine in the food or pharmaceutical industry.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Food Science & Technology
Ximing Yang, Shengnan Li, Chao Wang, Yuhang Lou, Xinxiu Xia, Hongyan Xu
Summary: The study showed that whole powder and polysaccharide from Sporisorium reilianum improved disease and colon tissue structure in mice with DSS-induced colitis. The composition and diversity of gut microbiota were significantly increased, promoting the recovery of intestinal mucosal structure. These findings suggest the potential of S. reilianum as a functional food to prevent colitis through the gut microbiota.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Biology
Jesus Gilberto Aramburo-Galvez, Raul Tinoco-Narez-Gil, Aldo Alejandro Arvizu-Flores, Oscar Gerardo Figueroa-Salcido, Jose Antonio Mora-Melgem, Alma Rosa Islas-Rubio, Lilian Karem Flores-Mendoza, Veronica Lopez-Teros, Humberto Astiazaran-Garcia, Feliznando Isidro Cardenas-Torres, Noe Ontiveros
Summary: The search for an animal model to assess the allergenic potential of processed food products is ongoing. Researchers evaluated sensitization to ovalbumin (OVA) in different structural states and the allergic response triggered after intra-gastric or food challenges. The proposed murine model of egg allergy holds the potential for evaluating the impact of food matrix composition and processing on the threshold of egg-allergic responses.