New understandings of the genetic basis of isolated idiopathic central hypogonadism

Nasal embryonic LHRH factor (NELF) mutations in patients with normosmic hypogonadotropic hypogonadism and Kallmann syndrome

(2011) Ning Xu et al.   FERTILITY AND STERILITY

A Genetic Basis for Functional Hypothalamic Amenorrhea

(2011) Lisa M. Caronia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism

(2011) J. Tornberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of the Single Copy Gonadotropin-Releasing Hormone Receptor in Mice by Gene Trap: Severe Reduction of Reproductive Organs and Functions in Developing and Adult Mice

(2010) Sheng Wu et al.   ENDOCRINOLOGY

Oligogenic basis of isolated gonadotropin-releasing hormone deficiency

(2010) G. P. Sykiotis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel insights in FGFR1 regulation: lessons from Kallmann syndrome

(2010) Youli Hu et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The recent genetics of hypogonadotrophic hypogonadism - novel insights and new questions

(2009) Robert K. Semple et al.   CLINICAL ENDOCRINOLOGY

CHD7mutations in patients initially diagnosed with Kallmann syndrome - the clinical overlap with CHARGE syndrome

(2009) MCJ Jongmans et al.   CLINICAL GENETICS

Hypogonadotropic Hypogonadism due to a Novel Missense Mutation in the First Extracellular Loop of the Neurokinin B Receptor

(2009) Tulay Guran et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Oestrogen, Kisspeptin, GPR54 and the Pre-Ovulatory Luteinising Hormone Surge

(2009) J. Clarkson et al.   JOURNAL OF NEUROENDOCRINOLOGY

Distribution of Kisspeptin Neurones in the Adult Female Mouse Brain

(2009) J. Clarkson et al.   JOURNAL OF NEUROENDOCRINOLOGY

The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism

(2009) Suzy D. C. Bianco et al.   Nature Reviews Endocrinology

Isolated Familial Hypogonadotropic Hypogonadism and aGNRH1Mutation

(2009) Jérôme Bouligand et al.   NEW ENGLAND JOURNAL OF MEDICINE

GNRH1mutations in patients with idiopathic hypogonadotropic hypogonadism

(2009) Yee-Ming Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in CHD7, Encoding a Chromatin-Remodeling Protein, Cause Idiopathic Hypogonadotropic Hypogonadism and Kallmann Syndrome

(2008) Hyung-Goo Kim et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fibroblast Growth Factor 8 Signaling through Fibroblast Growth Factor Receptor 1 Is Required for the Emergence of Gonadotropin-Releasing Hormone Neurons

(2008) Wilson C. J. Chung et al.   ENDOCRINOLOGY

Biallelic mutations in the prokineticin-2 gene in two sporadic cases of Kallmann syndrome

(2008) Chrystel Leroy et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

PROKR2 missense mutations associated with Kallmann syndrome impair receptor signalling activity

(2008) Carine Monnier et al.   HUMAN MOLECULAR GENETICS

Mutations inProkineticin 2andProkineticin receptor 2genes in Human Gonadotrophin-Releasing Hormone Deficiency: Molecular Genetics and Clinical Spectrum

(2008) Lindsay W. Cole et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice

(2008) John Falardeau et al.   JOURNAL OF CLINICAL INVESTIGATION

TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction

(2008) A Kemal Topaloglu et al.   NATURE GENETICS

Reproductive functions of kisspeptin and Gpr54 across the life cycle of mice and men

(2008) Yee-Ming Chan et al.   PEPTIDES

Menopause and the human hypothalamus: Evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback

(2008) Naomi E. Rance   PEPTIDES