Article
Engineering, Biomedical
Antony P. Mcnamee, Tia A. Griffith, Amanda G. Smith, Lennart Kuck, Michael J. Simmonds
Summary: This study investigated the feasibility of accelerating hemocompatibility testing by standardizing the number of pump exposures, and assessed hemolysis and von Willebrand Factor degradation in three different volume blood loops.
Article
Computer Science, Information Systems
Igor Nesterenko, Alexander A. Pugovkin, Steffen Leonhardt, Marian Walter, Patrick Borchers, Aleksandr Markov, Jamshid H. Karimov, Sergey Selishchev, Dmitry Telyshev
Summary: This work theoretically investigated the electric machine of implantable axial-flow rotary blood pumps (RBPs), describing the electromagnetic coupling of rotor and stator with Maxwell's equations in a simplified model. The estimated upper limit of error introduced by simplifications was less than 0.2%, indicating the finite accuracy of the description and its influence on the control signal. The key features of the electric machine in axial-flow RBPs were identified, including the tendency of back electromotive force signal to be sinusoidal and the optimal waveform of control signal being sinusoidal.
Article
Engineering, Biomedical
Mario Klein, Jana Christine Tack, Ilona Mager, Judith Maas, Thomas Schmitz-Rode, Jutta Arens, Ulrich Steinseifer, Johanna Charlotte Clauser
Summary: This feasibility study investigated if the method of thromboelastometry (TEM) is able to assess coagulation kinematics under the in vitro conditions of rotary blood pump (RBP) tests. The results showed visible thrombus formation in some pumps, but most of the thromboelastometry results did not provide clear indications. However, the TEM clotting time obtained by non-anticoagulated blood appeared to be more sensitive for the activation of coagulation in vitro.
BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK
(2022)
Article
Engineering, Biomedical
Zhehuan Tan, Mingming Huo, Kairong Qin, Ayman S. El-Baz, Palaniappan Sethu, Yu Wang, Guruprasad A. Giridharan
Summary: A sensorless, physiologic feedback control strategy was developed for continuous flow rotary blood pumps (RBP) to adjust pump speed and avoid suction, diminish vascular pulsatility, and reduce risk of adverse events during varying physical activities.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2023)
Article
Physiology
Ping Li, Xu Mei, Wanning Ge, Tingting Wu, Min Zhong, Nana Huan, Qiubo Jiang, Po-Lin Hsu, Ulrich Steinseifer, Nianguo Dong, Liudi Zhang
Summary: The purpose of this study was to evaluate the hemocompatibility of blood pumps and the blood damage under different operating conditions. The results showed that the magnetically levitated centrifugal blood pump had better in vitro hemocompatibility compared to the mechanically supported blood pumps.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Agricultural Engineering
Mahdi Rashvand, Giuseppe Altieri, Zhiguo li, Abbas Akbarnia, Francesco Genovese, Attilio Matera, Giovanni Carlo Di Renzo
Summary: This research investigates the mechanical damage to olive fruit caused by a rotary olive harvesting machine. The study explores the influence of impactor rod geometrical properties and speed on the damage. The findings have significant implications for the design and optimization of such harvesting machines.
BIOSYSTEMS ENGINEERING
(2023)
Article
Multidisciplinary Sciences
Andreas Escher, Emanuel Johannes Hubmann, Barbara Karner, Barbara Messner, Gunther Laufer, Ulrich Kertzscher, Daniel Zimpfer, Marcus Granegger
Summary: This study applies computational fluid dynamics to analyze the hydraulic energy dissipation in rotodynamic blood pumps (RBPs) and compares it with hemolysis performance. The results show a strong correlation between hydraulic energy dissipation and hemolysis, which can be described as a function of shear stresses and exposure time.
ADVANCED THEORY AND SIMULATIONS
(2022)
Article
Physiology
Liang Wang, Zhong Yun, Jinfu Yao, Xiaoyan Tang, Yunhao Feng, Chuang Xiang
Summary: A novel hemolysis model is proposed in this study to more accurately predict the hemolysis value when designing axial flow blood pumps. The movement behavior of a single RBC in the shear flow field was simulated to determine the critical value of shear stress for physiological injury of RBCs and study the equivalent treatment of RBC aging. The validity of the model was verified under experimental conditions, and the results showed that the novel hemolysis model could effectively reduce the estimation error of the hemolysis value and provide a reference for optimal design of rotary vane blood pumps.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Engineering, Biomedical
Pascal Puentener, Marcel Schuck, Johann W. Kolar
Summary: The study conducted a comparative analysis of computational fluid dynamics simulations and in vitro hemolysis examinations of a bearingless centrifugal blood pump. Results showed that a double-stage model achieved the highest correlation, with cell destruction mainly occurring in the radial gap of the pump. Modifying design parameters can improve cell compatibility. The study highlights the limitations and benefits of using CFD models in interpreting in vitro test outcomes.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Biophysics
Thalita Cristina de Mello Costa, Rodolfo Chiari-Correia, Carlos Ernesto G. Salmon, Luiz Guilherme Darrigo-Junior, Carlos Eduardo S. Grecco, Fabiano Pieroni, Joana Teresa B. Faria, Ana Beatriz P. L. Stracieri, Juliana B. E. Dias, Daniela Aparecida de Moraes, Maria Carolina Oliveira, Renato Guerino-Cunha, Antonio Carlos Santos, Belinda P. Simoes
Summary: The study confirms the presence of white matter lesions in SCD patients and suggests that HSCT can promote recovery of brain injury with potential improvement in brain structural connectivity.
BONE MARROW TRANSPLANTATION
(2021)
Article
Engineering, Biomedical
Andreas Escher, Henrike Goebel, Marcel Nicolai, Thomas Schloeglhofer, Emanuel J. Hubmann, Gunther Laufer, Barbara Messner, Ulrich Kertzscher, Daniel Zimpfer, Marcus Granegger
Summary: This study compared the hemolytic profiles of two different models of rotodynamic blood pumps under different operating conditions. The results showed that an increase in pump speed was associated with increased hemolysis, while low flow conditions resulted in higher levels of hemolysis compared to high flow conditions. Computational fluid dynamics analysis revealed a correlation between hydraulic losses and hemolysis. However, predicting the clinical impact of different operating conditions using current hemolysis metrics is difficult.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2022)
Article
Hematology
Narges Hadjesfandiari, Katherine Serrano, Elena Levin, Parveen Johal, Shelley Feenstra, Andrew W. Shih, Dana Devine
Summary: Mechanical stress on red blood cells caused by infusion pumps can lead to hemolysis, but the degree of hemolysis is minimal for all tested pumps and red blood cell conditions.
Article
Thermodynamics
Hongyan Shi, Bowen Lei, Jianhua Wu
Summary: This study experimentally and numerically investigated the lubricant properties of R290 rotary compressors used in low-temperature heat pumps and their impact on bearing oil film thickness. The findings suggest that POE68 is more suitable for low-temperature heat pumps than PAG40. It is recommended to adjust the viscosity of the lubricant under different environmental conditions to improve the performance and reliability of low-temperature heat pumps.
INTERNATIONAL JOURNAL OF REFRIGERATION
(2022)
Article
Geriatrics & Gerontology
Mohamad Gholizade, Akram Farhadi, Maryam Marzban, Mehdi Mahmudpour, Iraj Nabipour, Mohammadreza Kalantarhormozi, Gita Shafiee, Afshin Ostovar, Bagher Larijani, Amir Hossein Darabi, Eisa Safavi
Summary: This study found that platelet count and platelet to white blood cell ratio were associated with sarcopenia after accounting for confounding factors, while white blood cell count was not. There were gender differences in the relationship between sarcopenia parameters.
Article
Computer Science, Information Systems
Achmad Abdurrazzaq, Ahmad Kadri Junoh, Zainab Yahya, Ismail Mohd
Summary: A new detection technique for white blood cells is proposed in this study, which directly considers the features of white blood cells using singular value decomposition approach and performs better than existing methods. Existing methods only work well for white blood cells with dense color intensities, while the proposed method works well overall by comparing the level of similarity in white blood cells.
MULTIMEDIA TOOLS AND APPLICATIONS
(2021)