Transient Receptor Potential Ankyrin 1 Receptor Stimulation by Hydrogen Peroxide Is Critical to Trigger Pain During Monosodium Urate-Induced Inflammation in Rodents

The functions of TRPA1 and TRPV1: moving away from sensory nerves

(2012) ES Fernandes et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Experience and Impact of Living With Gout

(2012) Karen Lindsay et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Hypoxia-inducible Factor-1α (HIF1α) Switches on Transient Receptor Potential Ankyrin Repeat 1 (TRPA1) Gene Expression via a Hypoxia Response Element-like Motif to Modulate Cytokine Release

(2012) Noriyuki Hatano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uric acid as a danger signal in gout and its comorbidities

(2012) Kenneth L. Rock et al.   Nature Reviews Rheumatology

Inflammatory Gout: Observations over a Half-Century

(2011) Stephen E. Malawista et al.   FASEB JOURNAL

Transient receptor potential channels as therapeutic targets

(2011) Magdalene M. Moran et al.   NATURE REVIEWS DRUG DISCOVERY

Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats

(2011) Carin Hoffmeister et al.   PAIN

Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation

(2011) Romina Nassini et al.   PAIN

TRPA1 antagonists as potential analgesic drugs

(2011) E.L. Andrade et al.   PHARMACOLOGY & THERAPEUTICS

Reversible Ponceau staining as a loading control alternative to actin in Western blots

(2010) Isabel Romero-Calvo et al.   ANALYTICAL BIOCHEMISTRY

Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators

(2010) Nobuaki Takahashi et al.   Channels

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

(2010) Romina Nassini et al.   FASEB JOURNAL

Synergistic Role of TRPV1 and TRPA1 in Pancreatic Pain and Inflammation

(2010) Erica S. Schwartz et al.   GASTROENTEROLOGY

Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents

(2010) Pier Giovanni Baraldi et al.   JOURNAL OF MEDICINAL CHEMISTRY

TRPA1 Contributes to Cold Hypersensitivity

(2010) D. del Camino et al.   JOURNAL OF NEUROSCIENCE

Irritating channels: the case of TRPA1

(2010) Bernd Nilius et al.   JOURNAL OF PHYSIOLOGY-LONDON

Update on gout: new therapeutic strategies and options

(2010) Robert Terkeltaub   Nature Reviews Rheumatology

Transient receptor potential V1 regulates activation and modulation of transient receptor potential A1 by Ca2+

(2010) M.J. Patil et al.   NEUROSCIENCE

Inflammation, oxidative stress and lipids: the risk triad for atherosclerosis in gout

(2010) E. Krishnan   RHEUMATOLOGY

Mechanisms of inflammation in gout

(2010) Nathalie Busso et al.   ARTHRITIS RESEARCH & THERAPY

Human catalase: looking for complete identity

(2010) Madhur M. Goyal et al.   Protein & Cell

Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis

(2009) R Torres et al.   ANNALS OF THE RHEUMATIC DISEASES

TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1

(2009) Margaux M. Salas et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Gout

(2009) Pascal Richette et al.   LANCET

The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation

(2009) Diogo Santos M. da Costa et al.   PAIN

TRPV1 and TRPA1 Mediate Peripheral Nitric Oxide-Induced Nociception in Mice

(2009) Takashi Miyamoto et al.   PLoS One

Oxidative challenges sensitize the capsaicin receptor by covalent cysteine modification

(2009) H.-h. Chuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of transient receptor potential ankyrin 1 by hydrogen peroxide

(2008) Yosuke Sawada et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Receptor-Independent, Direct Membrane Binding Leads to Cell-Surface Lipid Sorting and Syk Kinase Activation in Dendritic Cells

(2008) Gilbert Ng et al.   IMMUNITY

Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress

(2008) D. A. Andersson et al.   JOURNAL OF NEUROSCIENCE

Pronociceptive response elicited by TRPA1 receptor activation in mice

(2008) E.L. Andrade et al.   NEUROSCIENCE

Hydrogen peroxide is a novel mediator of inflammatory hyperalgesia, acting via transient receptor potential vanilloid 1-dependent and independent mechanisms

(2008) Julie Elizabeth Keeble et al.   PAIN