The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon-γ and interleukin-17 production by human CD4+ T cells
出版年份 2011 全文链接
标题
The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon-γ and interleukin-17 production by human CD4+ T cells
作者
关键词
-
出版物
ARTHRITIS AND RHEUMATISM
Volume 64, Issue 6, Pages 1790-1798
出版商
Wiley
发表日期
2011-12-07
DOI
10.1002/art.34329
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)
- (2011) Kamran Ghoreschi et al. JOURNAL OF IMMUNOLOGY
- Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate
- (2011) Yoshiya Tanaka et al. ARTHRITIS CARE & RESEARCH
- Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium
- (2010) A. J. Hueber et al. JOURNAL OF IMMUNOLOGY
- Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis
- (2010) Debra M Meyer et al. Journal of Inflammation-London
- CP-690550, a Janus Kinase Inhibitor, Suppresses CD4+ T-Cell–Mediated Acute Graft-Versus-Host Disease by Inhibiting the Interferon-γ Pathway
- (2010) Hyung-Bae Park et al. TRANSPLANTATION
- Improved pain, physical functioning and health status in patients with rheumatoid arthritis treated with CP-690,550, an orally active Janus kinase (JAK) inhibitor: results from a randomised, double-blind, placebo-controlled trial
- (2009) J H Coombs et al. ANNALS OF THE RHEUMATIC DISEASES
- The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo
- (2009) Joel M. Kremer et al. ARTHRITIS AND RHEUMATISM
- Synovial fibroblasts spread rheumatoid arthritis to unaffected joints
- (2009) Stephanie Lefèvre et al. NATURE MEDICINE
- Tyrosine kinases as targets for the treatment of rheumatoid arthritis
- (2009) Christina D'Aura Swanson et al. Nature Reviews Rheumatology
- Inhibitory effect of CD147/HAb18 monoclonal antibody on cartilage erosion and synovitis in the SCID mouse model for rheumatoid arthritis
- (2009) J. Jia et al. RHEUMATOLOGY
- The Effect of the JAK Inhibitor CP-690,550 on Peripheral Immune Parameters in Stable Kidney Allograft Patients
- (2009) Evelien A. F. J. van Gurp et al. TRANSPLANTATION
- Tyrosine kinases as targets in rheumatoid arthritis
- (2008) Antonio G. Tristano INTERNATIONAL IMMUNOPHARMACOLOGY
- A quantitative analysis of kinase inhibitor selectivity
- (2008) Mazen W Karaman et al. NATURE BIOTECHNOLOGY
- Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis
- (2008) Anthony J Milici et al. ARTHRITIS RESEARCH & THERAPY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started