The role of interleukin-1β in arthritic pain: Main involvement in thermal, but not mechanical, hyperalgesia in rat antigen-induced arthritis

Articular inflammation is controlled by myeloid cell-derived interleukin 1 receptor antagonist during the acute phase of arthritis in mice

(2011) Céline Lamacchia et al.   ANNALS OF THE RHEUMATIC DISEASES

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats

(2011) Carin Hoffmeister et al.   PAIN

Blockade of TNF-α rapidly inhibits pain responses in the central nervous system

(2011) Andreas Hess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integration of efficacy, pharmacokinetic and safety assessment of interleukin-1 receptor antagonist in a preclinical model of arthritis

(2011) Anne-Marie Zuurmond et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Tumor necrosis factor causes persistent sensitization of joint nociceptors to mechanical stimuli in rats

(2010) Frank Richter et al.   ARTHRITIS AND RHEUMATISM

The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis

(2010) Jan Bondeson et al.   ARTHRITIS AND RHEUMATISM

GRK2: A Novel Cell-Specific Regulator of Severity and Duration of Inflammatory Pain

(2010) N. Eijkelkamp et al.   JOURNAL OF NEUROSCIENCE

Validation of the digital pressure application measurement (PAM) device for detection of primary mechanical hyperalgesia in rat and mouse antigen-induced knee joint arthritis

(2010) J. Leuchtweis et al.   METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

Molecular effects of interleukin-1β on dorsal root ganglion neurons: Prevention of ligand-induced internalization of the bradykinin 2 receptor and downregulation of G protein-coupled receptor kinase 2

(2010) Gisela Segond von Banchet et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

TNFα Mechanically Sensitizes Masseter Muscle Afferent Fibers of Male Rats

(2009) Akhlaq W. Hakim et al.   JOURNAL OF NEUROPHYSIOLOGY

Experimental arthritis causes tumor necrosis factor-α-dependent infiltration of macrophages into rat dorsal root ganglia which correlates with pain-related behavior

(2009) Gisela Segond von Banchet et al.   PAIN

RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFα or anti-IL-1 therapies

(2009) Marina Stolina et al.   ARTHRITIS RESEARCH & THERAPY

Antinociceptive effects of tumor necrosis factor α neutralization in a rat model of antigen-induced arthritis: Evidence of a neuronal target

(2008) Michael K. Boettger et al.   ARTHRITIS AND RHEUMATISM

Nociceptors Are Interleukin-1  Sensors

(2008) A. M. Binshtok et al.   JOURNAL OF NEUROSCIENCE

Effect of cytokines on neuronal excitability

(2008) Maria Schäfers et al.   NEUROSCIENCE LETTERS

IL-1β signaling is required for mechanical allodynia induced by nerve injury and for the ensuing reduction in spinal cord neuronal GRK2

(2007) Wendy Kleibeuker et al.   BRAIN BEHAVIOR AND IMMUNITY