Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: Results of a phase II, randomized, placebo-controlled, dose-finding trial

Cutting Edge: The Dependence of Plasma Cells and Independence of Memory B Cells on BAFF and APRIL

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Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: Results of a phase II, randomized, placebo-controlled trial

(2011) R. F. van Vollenhoven et al.   ARTHRITIS AND RHEUMATISM

Biological therapy for lupus nephritis—tribulations and trials

(2010) Rona M. Smith et al.   Nature Reviews Rheumatology

Targeting B cells in immune-mediated inflammatory disease: A comprehensive review of mechanisms of action and identification of biomarkers

(2010) Thomas Dörner et al.   PHARMACOLOGY & THERAPEUTICS

B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B cell maturation antigen-immunoglobulin

(2010) Stacey R Dillon et al.   ARTHRITIS RESEARCH & THERAPY

Atacicept, a novel B cell-targeting biological therapy for the treatment of rheumatoid arthritis

(2009) C Bracewell et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Pharmacokinetics and immunoglobulin response of subcutaneous and intravenous atacicept in patients with systemic lupus erythematosus

(2009) I. Nestorov et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

Treatment of rheumatoid arthritis: state of the art 2009

(2009) Ronald F. van Vollenhoven   Nature Reviews Rheumatology

Synovial tissues concentrate secreted APRIL

(2009) Cem Gabay et al.   ARTHRITIS RESEARCH & THERAPY

Induction of macrophage secretion of tumor necrosis factor α through Fcγ receptor IIa engagement by rheumatoid arthritis–specific autoantibodies to citrullinated proteins complexed with fibrinogen

(2008) Cyril Clavel et al.   ARTHRITIS AND RHEUMATISM

Phase I Clinical Study of Atacicept in Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma

(2008) S. M. Ansell et al.   CLINICAL CANCER RESEARCH

Pharmacokinetics and Biological Activity of Atacicept in Patients With Rheumatoid Arthritis

(2008) Ivan Nestorov et al.   JOURNAL OF CLINICAL PHARMACOLOGY